A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10411
Swiss-prot Accession numberP04564 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismCapra hircus (Goat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Capra.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length34 Amino acids
Molecular weight3903
References1  PubMed abstract 3763441
Domain NameN/A
Hormone NameGastrin
Mature Hormone SequenceQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (18-34)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10414
Swiss-prot Accession numberP06885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 33) (G33); Gastrin].
Source organismCavia porcellus (Guinea pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length33 Amino acids
Molecular weight3757
References1  PubMed abstract 3747718
Domain NameN/A
Hormone NameGastrin
Mature Hormone SequenceQGPWAEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein16 Residues from position (18-33)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10432
Swiss-prot Accession numberP10034 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 33) (G33); Gastrin].
Source organismChinchilla brevicaudata (Chinchilla)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Chinchillidae; Chinchilla.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length33 Amino acids
Molecular weight3715
References1  PubMed abstract 3827930
Domain NameN/A
Hormone NameGastrin
Mature Hormone SequenceQGPWAEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein16 Residues from position (18-33)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10455
Swiss-prot Accession numberP33713 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 33) (G33); Gastrin].
Source organismDidelphis marsupialis virginiana (North American opossum)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Didelphis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length33 Amino acids
Molecular weight3856
References1  PubMed abstract 2361360
Domain NameN/A
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein16 Residues from position (18-33)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10456
Swiss-prot Accession numberP33714 (Sequence in FASTA format)
DescriptionGastrin.
Source organismMacaca mulatta (Rhesus macaque)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length17 Amino acids
Molecular weight2076
References1  PubMed abstract 2003150
Domain NameN/A
Hormone NameGastrin
Mature Hormone SequenceQGPWMEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (1-17)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number11149
Swiss-prot Accession numberP01354 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11482
References1  PubMed abstract 1773057
2  PubMed abstract 5784957
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number11151
Swiss-prot Accession numberP55885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length107 Amino acids
Molecular weight11884
References1  PubMed abstract 9716385
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEKEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (79-95)
ReceptorN/A
Gene ID100034214      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number11153
Swiss-prot Accession numberP01351 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11558
References1  PubMed abstract 6951161
2  PubMed abstract 6930858
3  PubMed abstract 14248711
4  PubMed abstract 14248712
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene ID445524      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number11155
Swiss-prot Accession numberO02686 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismOvis aries (Sheep)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11532
References1  PubMed abstract 9522119
2  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number11347
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 11

HMRbase accession number11351
Swiss-prot Accession numberP01352 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11573
References1  PubMed abstract 2608050
2  PubMed abstract 1773057
3  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP79266    Detail in HMRbase   
Gene ID280800      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 12

HMRbase accession number11353
Swiss-prot Accession numberP01353 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismCanis familiaris (Dog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11519
References1  PubMed abstract 2262079
2  PubMed abstract 3763441
3  PubMed abstract 5799207
4  PubMed abstract 2756156
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWMEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP30552    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 13

HMRbase accession number11365
Swiss-prot Accession numberP04563 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11832
References1  PubMed abstract 3453895
2  PubMed abstract 6897117
3  PubMed abstract 1701434
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQRPPMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP30553    Detail in HMRbase   
Gene ID25320      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 14

HMRbase accession number11465
Swiss-prot Accession numberP48757 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (G71); Big gastrin (Gastrin-34) (G34); Gastrin].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11607
References1  PubMed abstract 7488110
2  PubMed abstract 7492958
3  PubMed abstract 8647266
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceERPRMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP56481   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments