A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10008
Swiss-prot Accession numberQ9PU41 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityIn the small intestine, the major production site is around the vitelline diverticulum
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. It also decreases food intake and regulates gastrointestinal physiological processes.
Protein Length130 Amino acids
Molecular weight14091
References1  PubMed abstract 11072120
2  PubMed abstract 3620999
3  PubMed abstract 8355559
4  PubMed abstract 8637413
5  PubMed abstract 9039026
6  PubMed abstract 10069039
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQQPAGSHDGSPVAAELQQSLTEPHRHSRAPSSAGPLKPAPRLDGSFEQRATIGALLAKYLQQARKGSTGRFSVLGNRVQSIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein110 Residues from position (21-130)
ReceptorQ7T1P8    Detail in HMRbase   
Gene ID414884      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 2

HMRbase accession number10279
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-18
Mature Hormone SequenceLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein18 Residues from position (86-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10280
Swiss-prot Accession numberQ9PU29 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismStruthio camelus (Ostrich)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Palaeognathae; Struthioniformes; Struthionidae; Struthio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityHighly concentrated in the duodenum. Also localized in more distal parts of the small intestine
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14273
References1  PubMed abstract 11072120
Domain NameGastrin  
Hormone NameCholecystokinin-70
Mature Hormone SequenceAPSSAGPLKPVPRLDGSIDQRANIGALLAKYLQQARKGPTGRISVMGNRVQSIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein70 Residues from position (49-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10281
Swiss-prot Accession numberQ9PU29 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismStruthio camelus (Ostrich)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Palaeognathae; Struthioniformes; Struthionidae; Struthio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityHighly concentrated in the duodenum. Also localized in more distal parts of the small intestine
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14273
References1  PubMed abstract 11072120
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (111-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10282
Swiss-prot Accession numberQ9PU29 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismStruthio camelus (Ostrich)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Palaeognathae; Struthioniformes; Struthionidae; Struthio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityHighly concentrated in the duodenum. Also localized in more distal parts of the small intestine
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14273
References1  PubMed abstract 11072120
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (112-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10283
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-40
Mature Hormone SequenceYLQQARKGPTGRISMMGNRVQNIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein40 Residues from position (79-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10284
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceGPTGRISMMGNRVQNIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (86-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10285
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (111-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10286
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (112-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10297
Swiss-prot Accession numberP04563 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11832
References1  PubMed abstract 3453895
2  PubMed abstract 6897117
3  PubMed abstract 1701434
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGPQGPQHFIADLSKKQRPPMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP30553    Detail in HMRbase   
Gene ID25320      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 11

HMRbase accession number10360
Swiss-prot Accession numberQ9PU41 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityIn the small intestine, the major production site is around the vitelline diverticulum
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. It also decreases food intake and regulates gastrointestinal physiological processes.
Protein Length130 Amino acids
Molecular weight14091
References1  PubMed abstract 11072120
2  PubMed abstract 3620999
3  PubMed abstract 8355559
4  PubMed abstract 8637413
5  PubMed abstract 9039026
6  PubMed abstract 10069039
Domain NameGastrin  
Hormone NameCholecystokinin-70
Mature Hormone SequenceAPSSAGPLKPAPRLDGSFEQRATIGALLAKYLQQARKGSTGRFSVLGNRVQSIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein70 Residues from position (49-118)
ReceptorQ7T1P8    Detail in HMRbase   
Gene ID414884      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 12

HMRbase accession number10361
Swiss-prot Accession numberQ9PU41 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityIn the small intestine, the major production site is around the vitelline diverticulum
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. It also decreases food intake and regulates gastrointestinal physiological processes.
Protein Length130 Amino acids
Molecular weight14091
References1  PubMed abstract 11072120
2  PubMed abstract 3620999
3  PubMed abstract 8355559
4  PubMed abstract 8637413
5  PubMed abstract 9039026
6  PubMed abstract 10069039
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (111-118)
ReceptorQ7T1P8    Detail in HMRbase   
Gene ID414884      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 13

HMRbase accession number10362
Swiss-prot Accession numberQ9PU41 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismGallus gallus (Chicken)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityIn the small intestine, the major production site is around the vitelline diverticulum
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. It also decreases food intake and regulates gastrointestinal physiological processes.
Protein Length130 Amino acids
Molecular weight14091
References1  PubMed abstract 11072120
2  PubMed abstract 3620999
3  PubMed abstract 8355559
4  PubMed abstract 8637413
5  PubMed abstract 9039026
6  PubMed abstract 10069039
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (112-118)
ReceptorQ7T1P8    Detail in HMRbase   
Gene ID414884      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 14

HMRbase accession number11148
Swiss-prot Accession numberP01354 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11482
References1  PubMed abstract 1773057
2  PubMed abstract 5784957
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGPPQQVADLSKKQGPWLEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number11149
Swiss-prot Accession numberP01354 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11482
References1  PubMed abstract 1773057
2  PubMed abstract 5784957
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11150
Swiss-prot Accession numberP55885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length107 Amino acids
Molecular weight11884
References1  PubMed abstract 9716385
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGSPHLVADLSKKQGPWLEKEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (62-95)
ReceptorN/A
Gene ID100034214      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number11151
Swiss-prot Accession numberP55885 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length107 Amino acids
Molecular weight11884
References1  PubMed abstract 9716385
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEKEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (79-95)
ReceptorN/A
Gene ID100034214      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number11152
Swiss-prot Accession numberP01351 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11558
References1  PubMed abstract 6951161
2  PubMed abstract 6930858
3  PubMed abstract 14248711
4  PubMed abstract 14248712
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGPPHLVADLAKKQGPWMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorN/A
Gene ID445524      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number11153
Swiss-prot Accession numberP01351 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11558
References1  PubMed abstract 6951161
2  PubMed abstract 6930858
3  PubMed abstract 14248711
4  PubMed abstract 14248712
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene ID445524      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number11154
Swiss-prot Accession numberO02686 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismOvis aries (Sheep)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11532
References1  PubMed abstract 9522119
2  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQDPPHMVADLSKKQGPWVEEEEAAYGWM
Position of mature hormone in Pre-Hormone protein Residues from position 34
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 21

HMRbase accession number11155
Swiss-prot Accession numberO02686 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismOvis aries (Sheep)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11532
References1  PubMed abstract 9522119
2  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 22

HMRbase accession number11163
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceLSLPAVSEDGGQSDLGIVMEHTRHTRAAPSSGQLSLLSKAEDDEEPRSSLTELLARIISTKGTYRRSPSPKSKSMGNNHRIKDRDYLGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein104 Residues from position (20-123)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 23

HMRbase accession number11164
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-18
Mature Hormone SequenceLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein18 Residues from position (86-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 24

HMRbase accession number11165
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin 69
Mature Hormone SequenceHTRAAPSSGQLSLLSKAEDDEEPRSSLTELLARIISTKGTYRRSPSPKSKSMGNNHRIKDRDYLGWMDF
Position of mature hormone in Pre-Hormone protein69 Residues from position (43-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 25

HMRbase accession number11166
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin 36
Mature Hormone SequenceIISTKGTYRRSPSPKSKSMGNNHRIKDRDYLGWMDF
Position of mature hormone in Pre-Hormone protein36 Residues from position (76-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 26

HMRbase accession number11167
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin 26
Mature Hormone SequenceSPSPKSKSMGNNHRIKDRDYLGWMDF
Position of mature hormone in Pre-Hormone protein26 Residues from position (86-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 27

HMRbase accession number11168
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin 12
Mature Hormone SequenceIKDRDYLGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (100-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 28

HMRbase accession number11169
Swiss-prot Accession numberO93464 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK8) [Contains: Cholecystokinin 8 (CCK8);Cholecystokinin 12 (CCK12); Cholecystokinin 26 (CCK26);Cholecystokinin 36 (CCK36); Cholecystokinin 69 (CCK69)].
Source organismCarassius auratus (Goldfish)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
Subcellular locationSecreted (Potential)
Developmental StageExpression in the brain shows variation throughout the seasonal sexual cycle; in the optic tectum-thalamus of females, expression levels are lower in early gonadal recrudescence (October) compared to other sexual stages. In males, expression is high in the olfactory bulbs in early gonadal recrudescence and low in the posterior brain in late gonadal recrudescence (January). Expression is higher in females than males in the telencephalon-preoptic region and posterior brain during late gonadal recrudescence, and in the olfactory bulbs and optic tectum-thalamus during the sexually mature (April), and post-spawning and sexually regressed (July) stages.
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in the ovary, kidney, gill, gastrointestinal tract and pituitary. Differentially expressed in the brain in the optic tectum-thalamus, hypothalamus, telencephalon, olfactory bulb and tract, preoptic region and posterior brain region. Expression is strongest in the hypothalamus, where localization is to the posterior ventrolateral region. Expression in the brain is transiently increased 2 hours after feeding. Abundant in the sensory layers of the vagal lobe and along the border of the sensory region of the lobe and the deep fiber laye. Also present in the facial lobe and throughout the glossopharyngeal lobe
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut (By similarity). Induces the secretion of gonadotropin and growth hormone from the pituitary. Suppresses food intake and decreases the expression of preprosomatostatin genes in the forebrain
Protein Length123 Amino acids
Molecular weight13439
References1  PubMed abstract 9493851
2  PubMed abstract 8262360
3  PubMed abstract 8092330
4  PubMed abstract 10640690
5  PubMed abstract 12124755
6  PubMed abstract 14751584
7  PubMed abstract 15256279
Domain NameGastrin  
Hormone NameCholecystokinin 8
Mature Hormone SequenceDYLGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (104-111)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 29

HMRbase accession number11170
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVPPAEPAGSGLQRAEEAPRRQLRAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 30

HMRbase accession number11171
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (46-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 31

HMRbase accession number11172
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-58 desnonopeptide
Mature Hormone SequenceAVQRTDGESRAHLGALLARYIQQARKAPSGRMSIIKNLQNLDPSHRISD
Position of mature hormone in Pre-Hormone protein49 Residues from position (46-94)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 32

HMRbase accession number11173
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 33

HMRbase accession number11174
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQARKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (65-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 34

HMRbase accession number11175
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 35

HMRbase accession number11176
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-25
Mature Hormone SequenceIIKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein25 Residues from position (79-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 36

HMRbase accession number11177
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 37

HMRbase accession number11178
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 38

HMRbase accession number11179
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (97-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 39

HMRbase accession number11180
Swiss-prot Accession numberP23362 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMacaca fascicularis (Crab eating macaque) (Cynomolgus monkey)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12665
References1  PubMed abstract 2174979
2   "DNA sequences of macaque genes expressed in brain or testis and itsevolutionary implications."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
Domain NameGastrin  
Hormone NameCholecystokinin-5
Mature Hormone SequenceGWMDF
Position of mature hormone in Pre-Hormone protein5 Residues from position (99-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 40

HMRbase accession number11181
Swiss-prot Accession numberO57312 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 8 (CCK8)].
Source organismParalichthys olivaceus (Japanese flounder)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length135 Amino acids
Molecular weight14773
References1  PubMed abstract 11042006
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceHPISSQHLDEGQRSISTPSEALLEADTHSLGEPHLRQSRSAPQLKSLPVAEEDGDSRANLSELLARLISSRKGSVRRNSTAYSKGLSPNHRIADRDYLGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein115 Residues from position (21-135)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 41

HMRbase accession number11182
Swiss-prot Accession numberO57312 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 8 (CCK8)].
Source organismParalichthys olivaceus (Japanese flounder)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins (By similarity).
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length135 Amino acids
Molecular weight14773
References1  PubMed abstract 11042006
Domain NameGastrin  
Hormone NameCholecystokinin 8
Mature Hormone SequenceDYLGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (116-123)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 42

HMRbase accession number11183
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVPPADSAVPGAQEEEAHRRQLRAVQKVDGESRAHLGALLARYIQQARKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDFGRRSAEEYEYTS
Position of mature hormone in Pre-Hormone protein94 Residues from position (21-114)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 43

HMRbase accession number11184
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceAVQKVDGESRAHLGALLARYIQQARKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (45-102)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 44

HMRbase accession number11185
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQARKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (64-102)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 45

HMRbase accession number11186
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRVSMIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (70-102)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 46

HMRbase accession number11187
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (91-102)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 47

HMRbase accession number11188
Swiss-prot Accession numberP01356 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificitySynthesized in both cerebral cortex and duodenal mucosa
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins. Brain contains CCK-octapeptide (CCK8) and several CCK-desoctapeptides; whereas pig gut contains intact CCK33, CCK39, and CCK58 as well as CCK-octapeptide and the CCK- desoctapeptides. Distribution differences are due to tissue- specific post-translational processing events.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
Protein Length114 Amino acids
Molecular weight12526
References1  PubMed abstract 6205394
2   Mutt V., Jorpes J.E.; Submitted (AUG-1970) to the PIR data bank.
3  PubMed abstract 5410106
4  PubMed abstract 8443599
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (95-102)
ReceptorN/A
Gene ID397468      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 48

HMRbase accession number11189
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQQTVGSMNEDPGAREIEQQNILQHPRHIRASSSAQLKPFQRIDGTSDQKAVIGAMLAKYLQTRKAGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein110 Residues from position (21-130)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 49

HMRbase accession number11190
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceRIDGTSDQKAVIGAMLAKYLQTRKAGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (61-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 50

HMRbase accession number11191
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceGSSTGRYAVLPNRPVIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (86-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 51

HMRbase accession number11192
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (111-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 52

HMRbase accession number11193
Swiss-prot Accession numberP80344 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 33 (CCK33); Cholecystokinin 8 (CCK8);Cholecystokinin 7 (CCK7)].
Source organismRana catesbeiana (Bull frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, lung, testis and throughout the length of the small intestine. In the brain, expressed predominantly in the optic tectum and brain stem
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14449
References1  PubMed abstract 9075736
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (112-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 53

HMRbase accession number11194
Swiss-prot Accession numberQ9PU29 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 70(CCK70); Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismStruthio camelus (Ostrich)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Palaeognathae; Struthioniformes; Struthionidae; Struthio.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityHighly concentrated in the duodenum. Also localized in more distal parts of the small intestine
Post translational modification The precursor is cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14273
References1  PubMed abstract 11072120
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQQTAGSHNGNPLAAELEQSLTEHHRHVRAPSSAGPLKPVPRLDGSIDQRANIGALLAKYLQQARKGPTGRISVMGNRVQSIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein110 Residues from position (21-130)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 54

HMRbase accession number11195
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQQATGSHNENPVATELEQSLTEHHRHVRVPSSAGQLKPIQRLDGNVDQKANIGALLAKYLQQARKGPTGRISMMGNRVQNIDPTHRINDRDYMGWMDFGRRSAEEYEYSS
Position of mature hormone in Pre-Hormone protein110 Residues from position (21-130)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 55

HMRbase accession number11196
Swiss-prot Accession numberP80345 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 40 (CCK40); Cholecystokinin 33 (CCK33);Cholecystokinin 8 (CCK8); Cholecystokinin 7 (CCK7)].
Source organismTrachemys scripta (Red-eared slider turtle) (Pseudemys scripta)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Testudines; Cryptodira; Testudinoidea; Emydidae; Trachemys.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityExpressed in brain, duodenum and small intestine
Post translational modificationN/A
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear
Protein Length130 Amino acids
Molecular weight14603
References1  PubMed abstract 10561540
2  PubMed abstract 7925386
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceRLDGNVDQKANIGALLAKYLQQARKGPTGRISMMGNRVQNIDPTHRINDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (61-118)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 56

HMRbase accession number11344
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin-71
Mature Hormone SequenceSWKPRSQQPDAPLGTGANRDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein71 Residues from position (22-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 57

HMRbase accession number11345
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin-52
Mature Hormone SequenceDLELPWLEQQGPASHHRRQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein52 Residues from position (41-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 58

HMRbase accession number11346
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 59

HMRbase accession number11347
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 60

HMRbase accession number11348
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin-14
Mature Hormone SequenceWLEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein14 Residues from position (79-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 61

HMRbase accession number11349
Swiss-prot Accession numberP01350 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (Component I); Gastrin-52(G52); Big gastrin (Gastrin-34) (G34) (Component II); Gastrin(Gastrin-17) (G17) (Component III); Gastrin-14 (G14); Gastrin-6 (G6)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification Two different processing pathways probably exist in antral G- cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation of Tyr-87 blocks peptide degradation and enhances activity.
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11394
References1  PubMed abstract 3034736
2  PubMed abstract 6087340
3  PubMed abstract 6324077
4  PubMed abstract 6574456
5  PubMed abstract 6322186
6  PubMed abstract 6689486
7  PubMed abstract 15489334
8  PubMed abstract 8055952
9  PubMed abstract 5921183
10  PubMed abstract 2730647
11  PubMed abstract 5822140
12  PubMed abstract 7530658
13  PubMed abstract 11052986
Domain NameGastrin  
Hormone NameGastrin-6
Mature Hormone SequenceYGWMDF
Position of mature hormone in Pre-Hormone protein6 Residues from position (87-92)
ReceptorP32239    Detail in HMRbase   
Gene ID2520      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 62

HMRbase accession number11350
Swiss-prot Accession numberP01352 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11573
References1  PubMed abstract 2608050
2  PubMed abstract 1773057
3  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQDPPHMVADLSKKQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP79266    Detail in HMRbase   
Gene ID280800      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 63

HMRbase accession number11351
Swiss-prot Accession numberP01352 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11573
References1  PubMed abstract 2608050
2  PubMed abstract 1773057
3  PubMed abstract 5665711
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWVEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP79266    Detail in HMRbase   
Gene ID280800      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 64

HMRbase accession number11352
Swiss-prot Accession numberP01353 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismCanis familiaris (Dog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11519
References1  PubMed abstract 2262079
2  PubMed abstract 3763441
3  PubMed abstract 5799207
4  PubMed abstract 2756156
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGPPQLVADLSKKQGPWMEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP30552    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 65

HMRbase accession number11353
Swiss-prot Accession numberP01353 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismCanis familiaris (Dog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11519
References1  PubMed abstract 2262079
2  PubMed abstract 3763441
3  PubMed abstract 5799207
4  PubMed abstract 2756156
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWMEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP30552    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 66

HMRbase accession number11354
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceAVLRPDSEPRARLGALLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (46-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 67

HMRbase accession number11355
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (65-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 68

HMRbase accession number11356
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 69

HMRbase accession number11357
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin-22
Mature Hormone SequenceNLQGLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein22 Residues from position (82-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 70

HMRbase accession number11358
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 71

HMRbase accession number11359
Swiss-prot Accession numberP01355 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 39(CCK39); Cholecystokinin 33 (CCK33); Cholecystokinin 22 (CCK22);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityThe shortest form (CCK8) is predominantly found in the brain, whereas the larger ones are found in the intestine
Post translational modification Cholecystokinin, also known as CCK58, is proteolytically cleaved to produce a number of active cholecystokinins. Sulfation of Tyr-97 is essential for receptor activation.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12841
References1  PubMed abstract 2981840
2  PubMed abstract 6199787
3  PubMed abstract 3861130
4  PubMed abstract 6209267
5  PubMed abstract 12479974
6   Varro A., Young J., Gregory H., Csech J., Dockray G.J.; "Isolation, structure and properties of the C-terminal fragment of therat cholecystokinin precursor."; Regul. Pept. 15:195-195(1986).
7  PubMed abstract 8208365
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorP30553   Detail in HMRbase   
P30551    Detail in HMRbase   
Gene ID25298      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 72

HMRbase accession number11365
Swiss-prot Accession numberP04563 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11832
References1  PubMed abstract 3453895
2  PubMed abstract 6897117
3  PubMed abstract 1701434
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQRPPMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP30553    Detail in HMRbase   
Gene ID25320      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 73

HMRbase accession number11372
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVPPADPAGSGLQRAEEAPRRQLRVSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 74

HMRbase accession number11373
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceVSQRTDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (46-103)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 75

HMRbase accession number11374
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (65-103)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 76

HMRbase accession number11375
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 77

HMRbase accession number11376
Swiss-prot Accession numberP06307 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12669
References1  PubMed abstract 3856870
2   Kato K., Takahashi Y., Matsubara K.; "Molecular cloning of the human cholecystokinin gene."; Ann. N. Y. Acad. Sci. 448:613-615(1985).
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4   Livingston R.J., Rieder M.J., Chung M.-W., Ritchie T.K., Olson A.N.,Nguyen C.P., Nguyen D.A., Poel C.L., Robertson P.D., Schackwitz W.S.,Sherwood J.K., Sherwood A.M., Leithauser B.J., Nickerson D.A.; "NIEHS-SNPs, environmental genome project, NIEHS ES15478, Departmentof Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 11076522
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorP32239   Detail in HMRbase   
P32238    Detail in HMRbase   
Gene ID885      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 78

HMRbase accession number11390
Swiss-prot Accession numberP09240 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12866
References1  PubMed abstract 2011497
2  PubMed abstract 3862083
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPVVPAEATDPVEQRAEEAPRRQLRAVLRPDREPRARLGALLARYIQQVRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorP56481   Detail in HMRbase   
O08786   Detail in HMRbase   
Q3TPL0   Detail in HMRbase   
Q3ZB46   Detail in HMRbase   
Q3ZB53   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene ID12424      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 79

HMRbase accession number11391
Swiss-prot Accession numberP09240 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12866
References1  PubMed abstract 2011497
2  PubMed abstract 3862083
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorP56481   Detail in HMRbase   
O08786   Detail in HMRbase   
Q3TPL0   Detail in HMRbase   
Q3ZB46   Detail in HMRbase   
Q3ZB53   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene ID12424      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 80

HMRbase accession number11392
Swiss-prot Accession numberP09240 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12866
References1  PubMed abstract 2011497
2  PubMed abstract 3862083
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorP56481   Detail in HMRbase   
O08786   Detail in HMRbase   
Q3TPL0   Detail in HMRbase   
Q3ZB46   Detail in HMRbase   
Q3ZB53   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene ID12424      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 81

HMRbase accession number11393
Swiss-prot Accession numberP09240 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 33(CCK33); Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
Function This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12866
References1  PubMed abstract 2011497
2  PubMed abstract 3862083
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorP56481   Detail in HMRbase   
O08786   Detail in HMRbase   
Q3TPL0   Detail in HMRbase   
Q3ZB46   Detail in HMRbase   
Q3ZB53   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene ID12424      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 82

HMRbase accession number11445
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceQPMPHADPTGPRAQQAEEAPRRQLRAVPRVDDEPRAQLGALLARYIQQARKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDFGRRSAEEFEYTS
Position of mature hormone in Pre-Hormone protein95 Residues from position (21-115)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 83

HMRbase accession number11446
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-58
Mature Hormone SequenceAVPRVDDEPRAQLGALLARYIQQARKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein58 Residues from position (46-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 84

HMRbase accession number11447
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-58 desnonopeptide
Mature Hormone SequenceAVPRVDDEPRAQLGALLARYIQQARKAPSGRMSVIKNLQSLDPSHRISD
Position of mature hormone in Pre-Hormone protein49 Residues from position (46-94)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 85

HMRbase accession number11448
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-39
Mature Hormone SequenceYIQQARKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein39 Residues from position (65-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 86

HMRbase accession number11449
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-33
Mature Hormone SequenceKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein33 Residues from position (71-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 87

HMRbase accession number11450
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-25
Mature Hormone SequenceVIKNLQSLDPSHRISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein25 Residues from position (79-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 88

HMRbase accession number11451
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-12
Mature Hormone SequenceISDRDYMGWMDF
Position of mature hormone in Pre-Hormone protein12 Residues from position (92-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 89

HMRbase accession number11452
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-8
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (96-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 90

HMRbase accession number11453
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-7
Mature Hormone SequenceYMGWMDF
Position of mature hormone in Pre-Hormone protein7 Residues from position (97-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
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Search Result - 91

HMRbase accession number11454
Swiss-prot Accession numberP41520 (Sequence in FASTA format)
DescriptionCholecystokinins precursor (CCK) [Contains: Cholecystokinin 58(CCK58); Cholecystokinin 39 (CCK39); Cholecystokinin 33 (CCK33);Cholecystokinin 12 (CCK12); Cholecystokinin 8 (CCK8)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification The precursor cleaved by enzymes to produce a number of active cholecystokinins.
FunctionThis peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion
Protein Length115 Amino acids
Molecular weight12835
References1   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2217909
3  PubMed abstract 4011954
Domain NameGastrin  
Hormone NameCholecystokinin-5
Mature Hormone SequenceGWMDF
Position of mature hormone in Pre-Hormone protein5 Residues from position (99-103)
ReceptorP79266    Detail in HMRbase   
Gene ID617510      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 92

HMRbase accession number11463
Swiss-prot Accession numberP48757 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (G71); Big gastrin (Gastrin-34) (G34); Gastrin].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11607
References1  PubMed abstract 7488110
2  PubMed abstract 7492958
3  PubMed abstract 8647266
Domain NameGastrin  
Hormone NameGastrin-71
Mature Hormone SequenceSWKPRSQLQDASSGPGTNEDLEQRQFNKLGSASHHRRQLGLQGPQHFIADLSKKERPRMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein71 Residues from position (22-92)
ReceptorP56481   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 93

HMRbase accession number11464
Swiss-prot Accession numberP48757 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (G71); Big gastrin (Gastrin-34) (G34); Gastrin].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11607
References1  PubMed abstract 7488110
2  PubMed abstract 7492958
3  PubMed abstract 8647266
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceGSASHHRRQLGLQGPQHFIADLSKKERPRMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorP56481   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 94

HMRbase accession number11465
Swiss-prot Accession numberP48757 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Gastrin-71 (G71); Big gastrin (Gastrin-34) (G34); Gastrin].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length101 Amino acids
Molecular weight11607
References1  PubMed abstract 7488110
2  PubMed abstract 7492958
3  PubMed abstract 8647266
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceERPRMEEEEEAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorP56481   Detail in HMRbase   
Q8BKF6    Detail in HMRbase   
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments


Search Result - 95

HMRbase accession number11471
Swiss-prot Accession numberP50144 (Sequence in FASTA format)
DescriptionCholecystokinin type 1 precursor [Contains: Cholecystokinin (CCK)].
Source organismXenopus laevis (African clawed frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityBrain, gastrointestinal tract and lung
Post translational modificationN/A
FunctionN/A
Protein Length123 Amino acids
Molecular weight13943
References1  PubMed abstract 7669225
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (104-111)
ReceptorP70031    Detail in HMRbase   
Gene ID378611      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 96

HMRbase accession number11472
Swiss-prot Accession numberP50145 (Sequence in FASTA format)
DescriptionCholecystokinin type 2 precursor [Contains: Cholecystokinin (CCK)].
Source organismXenopus laevis (African clawed frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityBrain and gastrointestinal tract
Post translational modificationN/A
FunctionN/A
Protein Length128 Amino acids
Molecular weight14201
References1  PubMed abstract 7669225
Domain NameGastrin  
Hormone NameCholecystokinin
Mature Hormone SequenceDYMGWMDF
Position of mature hormone in Pre-Hormone protein8 Residues from position (109-116)
ReceptorP70031    Detail in HMRbase   
Gene ID378612      
PDB IDN/A
Drugpediawiki
Comments