A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10233
Swiss-prot Accession numberQ6ZWY8 (Sequence in FASTA format)
DescriptionThymosin beta-10.
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5026
References1  PubMed abstract 16141072
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID100043712   19240      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10234
Swiss-prot Accession numberQ9I980 (Sequence in FASTA format)
DescriptionThymosin beta-10 (Thymb10).
Source organismTorpedo marmorata (Marbled electric ray)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Pristiorajea; Batoidea;Torpediniformes; Torpedinoidei; Torpedinidae; Torpedo.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight4916
References1   O'Regan S., Matz V., Cha N., Meunier F.M.; "Torpedo electric lobe cDNAs that suppress a choline metabolismmutation in yeast."; Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDFGEVASFDKSKLKKTDTEVKNTLPTKETIDQEKKAESS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10235
Swiss-prot Accession numberQ6S9C5 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismChinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Chinchillidae; Chinchilla.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Protein Length44 Amino acids
Molecular weight5053
References1   Erdos G., Hu F.Z., Donfack J., Ahmed A.I., Preston R.A., Hayes J.D.,Post J.C., Ehrlich G.D.; "The thymosin beta-4 gene is expressed in chinchilla middle earmucosa."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10236
Swiss-prot Accession numberQ7YRC3 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMacropus eugenii (Tammar wallaby)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5037
References1  PubMed abstract 15008146
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMGEIQKFNKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10237
Swiss-prot Accession numberQ7YRC3 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMacropus eugenii (Tammar wallaby)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5037
References1  PubMed abstract 15008146
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10238
Swiss-prot Accession numberP62326 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.; "Analysis of sequences obtained from constructed full-length bovinecDNA libraries."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
2   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
3  PubMed abstract 6940133
4  PubMed abstract 2915977
5  PubMed abstract 2253778
6  PubMed abstract 1551869
7  PubMed abstract 2261438
8  PubMed abstract 8269922
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene ID781334      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10239
Swiss-prot Accession numberQ95274 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1   Winteroe A.K., Fredholm M., Davies W.; "Evaluation and characterization of a porcine small intestine cDNAlibrary."; Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 16971568
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID733606      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10240
Swiss-prot Accession numberQ95274 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSeraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1   Winteroe A.K., Fredholm M., Davies W.; "Evaluation and characterization of a porcine small intestine cDNAlibrary."; Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 16971568
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene ID733606      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10241
Swiss-prot Accession numberQ5R7H8 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismPongo pygmaeus (Orangutan)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSeraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene ID100173314      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10242
Swiss-prot Accession numberQ5R7H8 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismPongo pygmaeus (Orangutan)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Protein Length44 Amino acids
Molecular weight5053
References1   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID100173314      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10243
Swiss-prot Accession numberQ9I955 (Sequence in FASTA format)
DescriptionThymosin beta-a.
Source organismCyprinus carpio (Common carp)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length46 Amino acids
Molecular weight5194
References1   Fujiki K., Nakao M., Shin D., Yano T.; "Molecular cloning of carp (Cyprinus carpio) thymosin beta a."; Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-a
Mature Hormone SequenceSDNPVKEEVQQFDKKCLKKTNTAEKNTLPTKEDIDQEKKAAEGGK
Position of mature hormone in Pre-Hormone protein45 Residues from position (2-46)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10244
Swiss-prot Accession numberQ9I954 (Sequence in FASTA format)
DescriptionThymosin beta-b.
Source organismCyprinus carpio (Common carp)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length43 Amino acids
Molecular weight4970
References1   Fujiki K., Nakao M., Shin D., Yano T.; "Molecular cloning of carp (Cyprinus carpio) thymosin beta b."; Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-b
Mature Hormone SequenceADKPDISEVSQFDKTKLKKTETQEKNTLPTKETIEQEKQCEA
Position of mature hormone in Pre-Hormone protein42 Residues from position (2-43)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number10245
Swiss-prot Accession numberQ9W7M8 (Sequence in FASTA format)
DescriptionThymosin beta.
Source organismDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length45 Amino acids
Molecular weight5208
References1  PubMed abstract 10068630
Domain NameThymosin  
Hormone NameThymosin beta
Mature Hormone SequenceADKPNMTEITSFDKTKLRKTETQEKNPLPTKETIEQERQGESTP
Position of mature hormone in Pre-Hormone protein44 Residues from position (2-45)
ReceptorN/A
Gene ID402820      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number11045
Swiss-prot Accession numberP21752 (Sequence in FASTA format)
DescriptionThymosin beta-10 (Thymosin beta-9) [Contains: Thymosin beta-8].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityDistributed in numerous types of tissues, including thymus, spleen, lung, liver and muscle
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length42 Amino acids
Molecular weight4805
References1   Gutierrez-Pabello J.A., Adams L.G.; "Bovine thymosin beta-10 full length cDNA sequence."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 6952223
3  PubMed abstract 3818171
4   Gallert B., Zarbock J., Voelter W., Holak T.A.; "A nuclear magnetic resonance and simulated annealing study ofthymosin beta-9 in solution."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.517-518, Escom Science Publishers, Leiden (1993).
5  PubMed abstract 9108730
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDLGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQAK
Position of mature hormone in Pre-Hormone protein41 Residues from position (2-42)
ReceptorN/A
Gene ID282385      
PDB ID1HJ0      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number11046
Swiss-prot Accession numberP21752 (Sequence in FASTA format)
DescriptionThymosin beta-10 (Thymosin beta-9) [Contains: Thymosin beta-8].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityDistributed in numerous types of tissues, including thymus, spleen, lung, liver and muscle
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length42 Amino acids
Molecular weight4805
References1   Gutierrez-Pabello J.A., Adams L.G.; "Bovine thymosin beta-10 full length cDNA sequence."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 6952223
3  PubMed abstract 3818171
4   Gallert B., Zarbock J., Voelter W., Holak T.A.; "A nuclear magnetic resonance and simulated annealing study ofthymosin beta-9 in solution."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.517-518, Escom Science Publishers, Leiden (1993).
5  PubMed abstract 9108730
Domain NameThymosin  
Hormone NameThymosin beta-8
Mature Hormone SequenceADKPDLGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQ
Position of mature hormone in Pre-Hormone protein39 Residues from position (2-40)
ReceptorN/A
Gene ID282385      
PDB ID1HJ0      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11047
Swiss-prot Accession numberP63314 (Sequence in FASTA format)
DescriptionThymosin beta-10.
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5026
References1   Takafuji V.A., Sharova L.V., Crisman M.V., Howard R.D.; "Equus caballus thymosin, beta 10 (TMSB10) mRNA."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
2   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID100033928      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 17

HMRbase accession number11048
Swiss-prot Accession numberP63313 (Sequence in FASTA format)
DescriptionThymosin beta-10.
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationCytoplasm
Developmental StageFound to decrease dramatically after birth.
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5026
References1  PubMed abstract 3365256
2  PubMed abstract 2169566
3  PubMed abstract 8425765
4   Condon M.R., Hall A.K.; "Human thymosin beta 10 gene: its characterization and nucleotidesequence."; Submitted (APR-1992) to the EMBL/GenBank/DDBJ databases.
5  PubMed abstract 15489334
6  PubMed abstract 16916647
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID9168      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 18

HMRbase accession number11049
Swiss-prot Accession numberP21753 (Sequence in FASTA format)
DescriptionThymosin beta-10 (Thymosin beta-9).
Source organismSus scrofa (Pig)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length42 Amino acids
Molecular weight4823
References1   Cai G., Chen Y., Wang C., Li J., Peng G., Zhang H.; "Generation and analysis of cDNA sequences derived from a porcineskeletal muscle library."; Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 2774558
3  PubMed abstract 2090639
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQAK
Position of mature hormone in Pre-Hormone protein41 Residues from position (2-42)
ReceptorN/A
Gene ID100037998      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 19

HMRbase accession number11050
Swiss-prot Accession numberP63312 (Sequence in FASTA format)
DescriptionThymosin beta-10.
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationCytoplasm
Developmental StageFound to decrease dramatically after birth.
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5026
References1  PubMed abstract 3606131
2  PubMed abstract 1988550
3  PubMed abstract 1744129
Domain NameThymosin  
Hormone NameThymosin beta-10
Mature Hormone SequenceADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID50665      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 20

HMRbase accession number11051
Swiss-prot Accession numberP26351 (Sequence in FASTA format)
DescriptionThymosin beta-11.
Source organismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length42 Amino acids
Molecular weight4820
References1   Sakai M., Kono T.; "The cDNA sequence of rainbow trout thymosin beta."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 1575682
3   Echner H., Yialouris P.P., Haritos A.A., Gruebler G., Voelter W.; "Structure and syntheses of thymosin beta-11 and beta-12."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.751-752, Escom Science Publishers, Leiden (1993).
Domain NameThymosin  
Hormone NameThymosin beta-11
Mature Hormone SequenceSDKPNLEEVASFDKTKLKKTETQEKNPLPTKETIEQEKQAS
Position of mature hormone in Pre-Hormone protein41 Residues from position (2-42)
ReceptorN/A
Gene ID100170202      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 21

HMRbase accession number11052
Swiss-prot Accession numberP33248 (Sequence in FASTA format)
DescriptionThymosin beta-12.
Source organismLateolabrax japonicus (Japanese sea perch) (Japanese sea bass)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Lateolabrax.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight4910
References1  PubMed abstract 1731637
Domain NameThymosin  
Hormone NameThymosin beta-12
Mature Hormone SequenceSDKPDISEVTSFDKTKLKKTETQEKNPLPSKETIEQEKAAATS
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 22

HMRbase accession number11053
Swiss-prot Accession numberP26352 (Sequence in FASTA format)
DescriptionThymosin beta-12.
Source organismOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length43 Amino acids
Molecular weight4891
References1  PubMed abstract 1575682
2   Echner H., Yialouris P.P., Haritos A.A., Gruebler G., Voelter W.; "Structure and syntheses of thymosin beta-11 and beta-12."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.751-752, Escom Science Publishers, Leiden (1993).
Domain NameThymosin  
Hormone NameThymosin beta-12
Mature Hormone SequenceSDKPDLAEVSNFDKTKLKKTETQEKNPLPTKETIEQEKQATA
Position of mature hormone in Pre-Hormone protein42 Residues from position (2-43)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 23

HMRbase accession number11054
Swiss-prot Accession numberO14604 (Sequence in FASTA format)
DescriptionThymosin beta-4, Y-chromosomal.
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityUbiquitous
Post translational modificationN/A
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5013
References1  PubMed abstract 9381176
2  PubMed abstract 12815422
3  PubMed abstract 15489334
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPGMAEIEKFDKSKLKKTETQEKNPLSSKETIEQERQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID100130227   9087      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 24

HMRbase accession number11055
Swiss-prot Accession numberP62326 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismBos taurus (Bovine)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.; "Analysis of sequences obtained from constructed full-length bovinecDNA libraries."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
2   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
3  PubMed abstract 6940133
4  PubMed abstract 2915977
5  PubMed abstract 2253778
6  PubMed abstract 1551869
7  PubMed abstract 2261438
8  PubMed abstract 8269922
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID781334      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 25

HMRbase accession number11056
Swiss-prot Accession numberQ6S9C5 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismChinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Chinchillidae; Chinchilla.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function
Protein Length44 Amino acids
Molecular weight5053
References1   Erdos G., Hu F.Z., Donfack J., Ahmed A.I., Preston R.A., Hayes J.D.,Post J.C., Ehrlich G.D.; "The thymosin beta-4 gene is expressed in chinchilla middle earmucosa."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 26

HMRbase accession number11057
Swiss-prot Accession numberP62327 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2   Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 27

HMRbase accession number11058
Swiss-prot Accession numberP62327 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta-4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismEquus caballus (Horse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1   Hoerger S., Gallert B., Kellerman J., Voelter W.; "Isolation and structural identification of beta-thymosins from equinetissue: development of a specific ELISA against thymosin beta-10(TBeta-10)."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.749-750, Escom Science Publishers, Leiden (1993).
2   Takafuji V.A., Crisman M.V., Seat K.L., Sharova L.V., Ward D.L.,Howard R.D.; "Expression analysis of equine interleukin-1b treated equine synoviumusing suppression subtractive hybridization analysis (SSH-PCR)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 28

HMRbase accession number11059
Swiss-prot Accession numberP62328 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) (Fx) [Contains: Hematopoietic systemregulatory peptide (Seraspenide)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityExpressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1  PubMed abstract 3500230
2  PubMed abstract 16010977
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 1999398
5  PubMed abstract 6548414
6  PubMed abstract 10848969
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID7114      
PDB ID1UY5      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 29

HMRbase accession number11060
Swiss-prot Accession numberP62328 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) (Fx) [Contains: Hematopoietic systemregulatory peptide (Seraspenide)].
Source organismHomo sapiens (Human)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityExpressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells
Post translational modificationN/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1  PubMed abstract 3500230
2  PubMed abstract 16010977
3   Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 1999398
5  PubMed abstract 6548414
6  PubMed abstract 10848969
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene ID7114      
PDB ID1UY5      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 30

HMRbase accession number11061
Swiss-prot Accession numberP20065 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityOriginally found in thymus but it is widely distributed in many tissues
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length50 Amino acids
Molecular weight5679
References1  PubMed abstract 2351831
2  PubMed abstract 2226839
3  PubMed abstract 8838802
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceMLLPATMSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein50 Residues from position (1-50)
ReceptorN/A
Gene IDN/A
PDB ID1T44      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 31

HMRbase accession number11062
Swiss-prot Accession numberP20065 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismMus musculus (Mouse)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityOriginally found in thymus but it is widely distributed in many tissues
Post translational modificationN/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length50 Amino acids
Molecular weight5679
References1  PubMed abstract 2351831
2  PubMed abstract 2226839
3  PubMed abstract 8838802
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (8-11)
ReceptorN/A
Gene IDN/A
PDB ID1T44      
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 32

HMRbase accession number11063
Swiss-prot Accession numberP34032 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismOryctolagus cuniculus (Rabbit)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityOriginally found in thymus but it is widely distributed in many tissues
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5037
References1  PubMed abstract 6838210
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceADKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 33

HMRbase accession number11064
Swiss-prot Accession numberP62329 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityOriginally found in thymus but it is widely distributed in many tissues
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5053
References1  PubMed abstract 2325669
2  PubMed abstract 6201851
3  PubMed abstract 3838131
4  PubMed abstract 15489334
5  PubMed abstract 6954532
6  PubMed abstract 3670309
7  PubMed abstract 16641100
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID81814      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 34

HMRbase accession number11065
Swiss-prot Accession numberP62329 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) [Contains: Hematopoietic system regulatorypeptide (Seraspenide)].
Source organismRattus norvegicus (Rat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityOriginally found in thymus but it is widely distributed in many tissues
Post translational modificationN/A
FunctionSeraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase
Protein Length44 Amino acids
Molecular weight5053
References1  PubMed abstract 2325669
2  PubMed abstract 6201851
3  PubMed abstract 3838131
4  PubMed abstract 15489334
5  PubMed abstract 6954532
6  PubMed abstract 3670309
7  PubMed abstract 16641100
Domain NameThymosin  
Hormone NameHematopoietic system regulatory peptide
Mature Hormone SequenceSDKP
Position of mature hormone in Pre-Hormone protein4 Residues from position (2-5)
ReceptorN/A
Gene ID81814      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 35

HMRbase accession number11066
Swiss-prot Accession numberP18758 (Sequence in FASTA format)
DescriptionThymosin beta-4 (T beta 4) (Thymosin beta 4Xen).
Source organismXenopus laevis (African clawed frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular locationCytoplasm
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificitySpleen, kidney, heart, and oocytes
Post translational modificationN/A
FunctionPlays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight5097
References1  PubMed abstract 1567461
2  PubMed abstract 3124756
Domain NameThymosin  
Hormone NameThymosin beta-4
Mature Hormone SequenceSDKPDMAEIEKFDKAKLKKTETQEKNPLPSKETIEQEKQTSES
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene ID399438      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 36

HMRbase accession number11067
Swiss-prot Accession numberQ9DET5 (Sequence in FASTA format)
DescriptionThymosin beta.
Source organismCoturnix coturnix japonica (Japanese quail)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Coturnix.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length45 Amino acids
Molecular weight5245
References1   Dathe V.E., Prols F., Brand-Saberi B.; Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Domain NameThymosin  
Hormone NameThymosin beta
Mature Hormone SequenceCDKPDLSEVEKFDKKKLKKTNTEEKNTLPSKETIEQEKECVKSS
Position of mature hormone in Pre-Hormone protein44 Residues from position (2-45)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 37

HMRbase accession number11068
Swiss-prot Accession numberQ9DFJ9 (Sequence in FASTA format)
DescriptionThymosin beta.
Source organismGillichthys mirabilis (Long-jawed mudsucker)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Gobioidei;Gobiidae; Gillichthys.
Subcellular locationCytoplasm (By similarity)
Developmental StageN/A
Similarity Belongs to the thymosin beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length44 Amino acids
Molecular weight4914
References1  PubMed abstract 11172064
Domain NameThymosin  
Hormone NameThymosin beta
Mature Hormone SequenceSDKPDVKEVESFDKTTLKKTTTNEKNTLPTKEVIEQEKSGGSD
Position of mature hormone in Pre-Hormone protein43 Residues from position (2-44)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated