A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10134
Swiss-prot Accession numberQ23755 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone 1 precursor [Contains: PDH precursor-related peptide 1; Pigment-dispersing hormone 1 (PDH 1)].
Source organismCallinectes sapidus (Blue crab)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;Eubrachyura; Portunoidea; Portunidae; Callinectes.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityEyestalk sinus gland
Post translational modificationN/A
Function Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length78 Amino acids
Molecular weight8539
References1  PubMed abstract 7999056
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone 1
Mature Hormone SequenceNSELINSILGLPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (58-75)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10135
Swiss-prot Accession numberP91963 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone type 1 precursor [Contains: PDH precursor-related peptide (PPRD); Pigment-dispersing hormone (PDH)].
Source organismPenaeus vannamei (Penoeid shrimp) (European white shrimp)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Litopenaeus.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityEyestalk
Post translational modificationN/A
FunctionThe pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length79 Amino acids
Molecular weight8561
References1  PubMed abstract 8630031
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSLLGIPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (59-76)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10136
Swiss-prot Accession numberQ23756 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone 2 precursor [Contains: PDH precursor-related peptide 2; Pigment-dispersing hormone 2 (PDH 2)].
Source organismCallinectes sapidus (Blue crab)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;Eubrachyura; Portunoidea; Portunidae; Callinectes.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityEyestalk sinus gland
Post translational modificationN/A
Function Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length78 Amino acids
Molecular weight8344
References1  PubMed abstract 7999056
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone 2
Mature Hormone SequenceNSELINSLLGISALMNEA
Position of mature hormone in Pre-Hormone protein18 Residues from position (58-75)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10137
Swiss-prot Accession numberP91964 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone type 2 precursor [Contains: PDH precursor-related peptide (PPRD); Pigment-dispersing hormone (PDH)].
Source organismPenaeus vannamei (Penoeid shrimp) (European white shrimp)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Litopenaeus.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityEyestalk
Post translational modificationN/A
FunctionThe pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length80 Amino acids
Molecular weight8670
References1  PubMed abstract 8630031
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSLLGIPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (60-77)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10138
Swiss-prot Accession numberQ9TWW7 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone (PDH).
Source organismProcambarus clarkii (Red swamp crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Procambarus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionCauses the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas
Protein Length18 Amino acids
Molecular weight1942
References1  PubMed abstract 1823925
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSILGLPKVMNEA
Position of mature hormone in Pre-Hormone protein18 Residues from position (1-18)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10697
Swiss-prot Accession numberP37085 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone A precursor [Contains: PDH precursor-related peptide (PRPP); Pigment-dispersing hormone A (PDH A) (Light-adapting distal retinal pigment hormone A) (DRPH A)].
Source organismOrconectes limosus (Spinycheek crayfish)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;Astacoidea; Cambaridae; Orconectes; Faxonius.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityOptical ganglia of the eyestalk
Post translational modificationN/A
FunctionCauses the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length76 Amino acids
Molecular weight8281
References1  PubMed abstract 8477858
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone A
Mature Hormone SequenceGPHKRNSELINSILGLPKVMNEA
Position of mature hormone in Pre-Hormone protein18 Residues from position (56-73)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10698
Swiss-prot Accession numberQ06202 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone precursor [Contains: PDH precursor-relatedpeptide (PRPP); Pigment-dispersing hormone (PDH) (Light-adaptingdistal retinal pigment hormone) (DRPH)].
Source organismCarcinus maenas (Common shore crab) (Green crab)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;Eubrachyura; Portunoidea; Portunidae; Carcinus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityExpressed in eyestalk tissue and cerebral ganglia
Post translational modificationN/A
Function Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator
Protein Length78 Amino acids
Molecular weight8557
References1  PubMed abstract 1282803
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSILGLPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (58-75)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10699
Swiss-prot Accession numberP01209 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone (PDH) (Light-adapting distal retinalpigment hormone) (DRPH).
Source organismPandalus borealis (Northern red shrimp)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Caridea; Pandaloidea;Pandalidae; Pandalus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityN/A
Post translational modification N/A
Function Causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas.
Protein Length18 Amino acids
Molecular weight1903
References1  PubMed abstract 952951
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSGMINSILGIPRVMTEA
Position of mature hormone in Pre-Hormone protein18 Residues from position (1-18)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10700
Swiss-prot Accession numberP08871 (Sequence in FASTA format)
DescriptionPigment-dispersing hormone (PDH) (Beta-PDH) (Light-adapting distalretinal pigment hormone) (DRPH).
Source organismUca pugilator (Atlantic sand fiddler crab) (Celuca pugilator)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;Eubrachyura; Ocypodoidea; Ocypodidae; Ocypodinae; Uca complex; Celuca.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the arthropod PDH family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionCauses the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas
Protein Length18 Amino acids
Molecular weight1928
References1  PubMed abstract 16593589
2  PubMed abstract 8472537
Domain NamePigment_DH  
Hormone NamePigment-dispersing hormone
Mature Hormone SequenceNSELINSILGLPKVMNDA
Position of mature hormone in Pre-Hormone protein18 Residues from position (1-18)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated