A database of hormones and their receptors |
|
|
|
|
|
|
HMRbase accession number | 20004 |
Swiss-prot Accession number | Q9NYK7 (Sequence in FASTA format) |
Description | CCK-B/gastrin receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 516 Amino acids |
Molecular weight | 55857 |
Domain Name | N/A |
References | 1 PubMed abstract 10913157 2 PubMed abstract 7887934 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20016 |
Swiss-prot Accession number | Q28928 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor)(Fragment). |
Source organism | Papio hamadryas (Hamadryas baboon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Papio. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
Protein Length | 126 Amino acids |
Molecular weight | 14217 |
Domain Name | N/A |
References | 1 PubMed abstract 8625902 2 PubMed abstract 8625902 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20021 |
Swiss-prot Accession number | P79108 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Bos indicus (Zebu) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling (By similarity). |
Protein Length | 634 Amino acids |
Molecular weight | 70980 |
Domain Name | N/A |
References | 1 Souza S.C., Wang X., Lobo R.B., Kopchick J.J.; "Bovine growth hormone receptor cDNA derived from Bos taurusindicus."; Submitted (JUL-1994) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20022 |
Swiss-prot Accession number | Q90375 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Columba livia (Domestic pigeon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Columbiformes; Columbidae; Columba. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling (By similarity). |
Protein Length | 611 Amino acids |
Molecular weight | 68851 |
Domain Name | N/A |
References | 1 Cheng C.H.K., Shaw P.C., Tsim K.W.K., Lau K.F.; "Molecular cloning of the entire coding sequence of pigeon growthhormone receptor cDNA by PCR techniques."; Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20023 |
Swiss-prot Accession number | Q9XSZ1 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Papio anubis (Olive baboon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Papio. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71407 |
Domain Name | N/A |
References | 1 PubMed abstract 10425448 |
Hormone | N/A |
Gene ID | 100126695 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20025 |
Swiss-prot Accession number | Q9MZ01 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Fragment). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis (By similarity). |
Protein Length | 121 Amino acids |
Molecular weight | 13583 |
Domain Name | N/A |
References | 1 Matteri R.L.; "Sus scrofa melanin-concentrating hormone (MCH) receptor."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20027 |
Swiss-prot Accession number | O57568 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha (Fragment). |
Source organism | Sparus aurata (Gilthead sea bream) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sparidae; Sparus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for triiodothyronine. |
Protein Length | 129 Amino acids |
Molecular weight | 14904 |
Domain Name | N/A |
References | 1 Llewellyn L., Power D.M., Ramsurn V.P., Sweeney G.E., Wigham T.; Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20034 |
Swiss-prot Accession number | Q5Y4N8 (Sequence in FASTA format) |
Description | EGF-like module-containing mucin-like hormone receptor-like 1precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 7 EGF-like domains. Contains 1 GPS domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Could be involved in cell-cell interactions (By similarity). |
Protein Length | 932 Amino acids |
Molecular weight | 102308 |
Domain Name | N/A |
References | 1 PubMed abstract 15578266 |
Hormone | N/A |
Gene ID | 316137 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20070 |
Swiss-prot Accession number | Q9Y618 (Sequence in FASTA format) |
Description | Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator ofretinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-,retinoic-acid-receptor-associated corepressor) (T3 receptor-associating factor) (TRAC) (CTG repeat protein 26) (SMAP270). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the N-CoR nuclear receptor corepressors family. Contains 2 SANT domains. |
Tissue Specificity | Ubiquitous. High levels of expression are detected in lung, spleen and brain. |
Post translational modification | N/A |
Function | Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. |
Protein Length | 2517 Amino acids |
Molecular weight | 274034 |
Domain Name | N/A |
References | 1 PubMed abstract 10077563 2 PubMed abstract 10097068 3 PubMed abstract 7566127 4 PubMed abstract 8813722 5 PubMed abstract 9225980 6 PubMed abstract 11331609 7 PubMed abstract 10809664 8 PubMed abstract 10944117 9 PubMed abstract 11931768 10 PubMed abstract 11739383 11 PubMed abstract 15302935 12 PubMed abstract 17081983 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | 1KKQ 1R2B 1XC5 2ODD |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20071 |
Swiss-prot Accession number | Q9WU42 (Sequence in FASTA format) |
Description | Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator ofretinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-,retinoic-acid-receptor-associated corepressor) (T3 receptor-associating factor) (TRAC). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the N-CoR nuclear receptor corepressors family. Contains 2 SANT domains. |
Tissue Specificity | Ubiquitous. Also widely expressed in early embryos. |
Post translational modification | N/A |
Function | Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. |
Protein Length | 2472 Amino acids |
Molecular weight | 270859 |
Domain Name | N/A |
References | 1 PubMed abstract 10077563 2 PubMed abstract 10097068 3 PubMed abstract 10640276 |
Hormone | N/A |
Gene ID | 20602 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20102 |
Swiss-prot Accession number | Q9N4Q7 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family member nhr-13. |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Orphan nuclear receptor. |
Protein Length | 425 Amino acids |
Molecular weight | 48592 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 2 Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 178696 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20120 |
Swiss-prot Accession number | Q9N4B8 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family member nhr-41. |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Nucleus (Potential) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | Seam cells, excretory cell, rectal epithelia, chemosensory neurons, gut, head/tail hypodermis. |
Post translational modification | N/A |
Function | Orphan nuclear receptor that may have a role in dauer formation. |
Protein Length | 615 Amino acids |
Molecular weight | 68029 |
Domain Name | N/A |
References | 1 PubMed abstract 14738886 2 PubMed abstract 9851916 3 Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20134 |
Swiss-prot Accession number | Q9NA51 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family member nhr-5. |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Nucleus (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Orphan nuclear receptor. |
Protein Length | 703 Amino acids |
Molecular weight | 78723 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 191717 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20194 |
Swiss-prot Accession number | Q9W6N4 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha. |
Source organism | Hippoglossus hippoglossus (Atlantic halibut) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Pleuronectidae; Hippoglossus. |
Subcellular location | Nucleus |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for triiodothyronine. |
Protein Length | 416 Amino acids |
Molecular weight | 47479 |
Domain Name | N/A |
References | 1 Llewellyn L., Nowell M.A., Ramsurn V.P., Wigham T., Sweeney G.E.,Kristjansson B., Halldorsson O.; "Molecular cloning and developmental expression of the halibut thyroidhormone receptor-alpha."; Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20226 |
Swiss-prot Accession number | Q7M4L8 (Sequence in FASTA format) |
Description | Melanocortin receptor 1. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34749 |
Domain Name | N/A |
References | 1 PubMed abstract 8060302 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20232 |
Swiss-prot Accession number | Q28516 (Sequence in FASTA format) |
Description | Insulin receptor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulinreceptor alpha subunit; Insulin receptor subunit beta] (Fragment). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; Single-pass type I membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. |
Tissue Specificity | N/A |
Post translational modification | Autophosphorylated on tyrosine residues in response to insulin (By similarity). |
Function | This receptor binds insulin and has a tyrosine-protein kinase activity. |
Protein Length | 210 Amino acids |
Molecular weight | 23607 |
Domain Name | N/A |
References | 1 PubMed abstract 8083370 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20244 |
Swiss-prot Accession number | Q76N37 (Sequence in FASTA format) |
Description | LH receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 728 Amino acids |
Molecular weight | 81092 |
Domain Name | N/A |
References | 1 PubMed abstract 9545511 |
Hormone | N/A |
Gene ID | 395776 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20255 |
Swiss-prot Accession number | Q9I8N7 (Sequence in FASTA format) |
Description | Thyrotropin receptor precursor. |
Source organism | Morone saxatilis (Striped bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Morone. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 779 Amino acids |
Molecular weight | 87401 |
Domain Name | N/A |
References | 1 PubMed abstract 11000515 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20258 |
Swiss-prot Accession number | Q9PVN9 (Sequence in FASTA format) |
Description | Gonadotropin receptor I. |
Source organism | Oncorhynchus rhodurus (amago) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 658 Amino acids |
Molecular weight | 72992 |
Domain Name | N/A |
References | 1 PubMed abstract 10558873 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20270 |
Swiss-prot Accession number | Q6WNV5 (Sequence in FASTA format) |
Description | Vasotocin receptor. |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 419 Amino acids |
Molecular weight | 47582 |
Domain Name | N/A |
References | 1 PubMed abstract 15291760 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20273 |
Swiss-prot Accession number | Q90YN1 (Sequence in FASTA format) |
Description | Pituitary vasotocin receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 425 Amino acids |
Molecular weight | 46227 |
Domain Name | N/A |
References | 1 PubMed abstract 12573805 |
Hormone | N/A |
Gene ID | 428263 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20275 |
Swiss-prot Accession number | Q9PTN7 (Sequence in FASTA format) |
Description | Vasotocin VT1 receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 370 Amino acids |
Molecular weight | 42434 |
Domain Name | N/A |
References | 1 PubMed abstract 10611061 |
Hormone | N/A |
Gene ID | 427860 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20282 |
Swiss-prot Accession number | Q6WNV4 (Sequence in FASTA format) |
Description | Mesotocin receptor. |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 384 Amino acids |
Molecular weight | 43815 |
Domain Name | N/A |
References | 1 PubMed abstract 15291760 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20290 |
Swiss-prot Accession number | Q9N297 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Gorilla gorilla gorilla (Lowland gorilla) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Gorilla. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 422 Amino acids |
Molecular weight | 46155 |
Domain Name | N/A |
References | 1 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20293 |
Swiss-prot Accession number | Q9N298 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 422 Amino acids |
Molecular weight | 46172 |
Domain Name | N/A |
References | 1 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 471533 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20294 |
Swiss-prot Accession number | Q9N296 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Pongo pygmaeus (Orangutan) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 422 Amino acids |
Molecular weight | 46122 |
Domain Name | N/A |
References | 1 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20302 |
Swiss-prot Accession number | Q9N2B7 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Gorilla gorilla gorilla (Lowland gorilla) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Gorilla. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 390 Amino acids |
Molecular weight | 43566 |
Domain Name | N/A |
References | 1 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20420 |
Swiss-prot Accession number | Q9N263 (Sequence in FASTA format) |
Description | 5-HT1D receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 377 Amino acids |
Molecular weight | 42040 |
Domain Name | N/A |
References | 1 Bhalla P., Saxena P.R., Wurch T., Pauwels P.J., Sharma H.S.; "Molecular cloning, sequence analysis, and pharmacology of a cDNAencoding porcine 5-HT1D receptor."; Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 397309 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20422 |
Swiss-prot Accession number | Q9VN38 (Sequence in FASTA format) |
Description | CG1056-PA, isoform A. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 868 Amino acids |
Molecular weight | 95065 |
Domain Name | N/A |
References | 1 PubMed abstract 10731132 2 PubMed abstract 16110336 3 PubMed abstract 12537568 4 PubMed abstract 12537572 5 PubMed abstract 12537573 6 PubMed abstract 12537574 7 Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8 Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9 FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10 Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 40575 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20455 |
Swiss-prot Accession number | Q49NQ7 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Mus spretus (Western wild mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 332 Amino acids |
Molecular weight | 36959 |
Domain Name | N/A |
References | 1 Reichwald K., Petz U., Klingenspor M., Platzer M.; "Analysis of Mc4r locus in DIO and DR mice."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20456 |
Swiss-prot Accession number | Q49NR1 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 332 Amino acids |
Molecular weight | 36989 |
Domain Name | N/A |
References | 1 Reichwald K., Petz U., Klingenspor M., Platzer M.; "Analysis of Mc4r locus in DIO and DR mice."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20457 |
Swiss-prot Accession number | Q49NR4 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor (Adult male diencephalon cDNA, RIKEN full-length enriched library, clone:9330016A10 product:melanocortin 4receptor, full insert sequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 332 Amino acids |
Molecular weight | 36959 |
Domain Name | N/A |
References | 1 Reichwald K., Petz U., Klingenspor M., Platzer M.; "Analysis of Mc4r locus in DIO and DR mice."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12477932 3 Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 10349636 5 PubMed abstract 16141072 6 PubMed abstract 16141073 7 PubMed abstract 12466851 8 PubMed abstract 11217851 9 PubMed abstract 11042159 10 PubMed abstract 11076861 11 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 17202 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20472 |
Swiss-prot Accession number | Q66XN3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Thamnophis sirtalis |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea;Colubridae; Natricinae; Thamnophis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35350 |
Domain Name | N/A |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20473 |
Swiss-prot Accession number | Q66XN7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Thamnophis sirtalis |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea;Colubridae; Natricinae; Thamnophis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35306 |
Domain Name | N/A |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20513 |
Swiss-prot Accession number | Q6UNS5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 321 Amino acids |
Molecular weight | 34689 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20514 |
Swiss-prot Accession number | Q6UNS7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 321 Amino acids |
Molecular weight | 34688 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20515 |
Swiss-prot Accession number | Q6UNS8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34620 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20516 |
Swiss-prot Accession number | Q6UNS9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34519 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20517 |
Swiss-prot Accession number | Q6UNT0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34693 |
Domain Name | N/A |
References | 1 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20532 |
Swiss-prot Accession number | Q75NA2 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35143 |
Domain Name | N/A |
References | 1 Wada A., Kunieda T., Nishimura M., Kakizoe-Ishida Y., Watanabe N.,Ohkawa K., Tsudzuki M.; "A Nucleotide Substitution Responsible for the Tawny Coat ColorMutation Carried by the MSKR Inbred Strain of Mice."; J. Hered. 96:145-149(2005).
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20533 |
Swiss-prot Accession number | Q75NA3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35226 |
Domain Name | N/A |
References | 1 Wada A., Kunieda T., Nishimura M., Kakizoe-Ishida Y., Watanabe N.,Ohkawa K., Tsudzuki M.; "A Nucleotide Substitution Responsible for the Tawny Coat ColorMutation Carried by the MSKR Inbred Strain of Mice."; J. Hered. 96:145-149(2005).
2 PubMed abstract 12477932 3 Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 17199 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20604 |
Swiss-prot Accession number | Q8MIN7 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor subtype 2 MCH-2R. |
Source organism | Mustela putorius (European polecat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;Mustelinae; Mustela. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 340 Amino acids |
Molecular weight | 38889 |
Domain Name | N/A |
References | 1 Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A., Hreniuk D.L.,Feighner S.D., Palyha O.C., Figueroa D.J., Austin C.P., Jiang M.M.,Yu H., Ito J., Ito M., Ito M., Guan X.M., Kanatani A.,Van der Ploeg L.H.T., Howard A.D.; "Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: Species-Specific Gene Expression."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20605 |
Swiss-prot Accession number | Q8MIN8 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor subtype 1 MCH-1R. |
Source organism | Mustela putorius (European polecat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae;Mustelinae; Mustela. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 353 Amino acids |
Molecular weight | 38936 |
Domain Name | N/A |
References | 1 Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A., Hreniuk D.L.,Feighner S.D., Palyha O.C., Figueroa D.J., Austin C.P., Jiang M.M.,Yu H., Ito J., Ito M., Ito M., Guan X.M., Kanatani A.,Van der Ploeg L.H.T., Howard A.D.; "Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: Species-Specific Gene Expression."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20626 |
Swiss-prot Accession number | Q703N6 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Bubalus bubalis (Domestic water buffalo) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bubalus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 328 Amino acids |
Molecular weight | 37741 |
Domain Name | N/A |
References | 1 Konwar R., Srivastava A.K.; "Expression of recombinant Buffalo pituitary gonadotropin-releasinghormone receptor (GnRH-R)."; Domest. Anim. Endocrinol. 0:0-0(2005).
2 Srivastava A.K.; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20688 |
Swiss-prot Accession number | Q8WN93 (Sequence in FASTA format) |
Description | Calcitonin receptor-like receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 462 Amino acids |
Molecular weight | 53656 |
Domain Name | N/A |
References | 1 PubMed abstract 11714898 |
Hormone | N/A |
Gene ID | 397172 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20809 |
Swiss-prot Accession number | Q3HNP5 (Sequence in FASTA format) |
Description | Beta 3-adrenoceptor. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity). |
Protein Length | 379 Amino acids |
Molecular weight | 40324 |
Domain Name | N/A |
References | 1 Lau Y.M., Au L.S., Seto S.W., Kwan Y.W., Tsui K.W., Liu W.K.; "Nitric oxide-mediated beta 3-adrenoceptor inhibition of basal L-typeCa2+ channels of guinea-pig single ventricular myocyte."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20810 |
Swiss-prot Accession number | Q3S2N8 (Sequence in FASTA format) |
Description | Alpha-1D adrenoreceptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium (By similarity). |
Protein Length | 514 Amino acids |
Molecular weight | 58032 |
Domain Name | N/A |
References | 1 Moon T.W., Perry S.F., Chen X.; "Molecular characterization of alpha-1 adrenoreceptor gene family androle in blood pressure regulation in rainbow trout (Oncorhynchusmykiss)."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100136679 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20874 |
Swiss-prot Accession number | Q6YNB6 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Macropus eugenii (Tammar wallaby) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 694 Amino acids |
Molecular weight | 78480 |
Domain Name | N/A |
References | 1 Mattiske D.M., Pask A.J., Shaw J.M., Shaw G.; "Structure and expression of the follicle-stimulating hormone receptorgene in a marsupial, Macropus eugenii."; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
2 Mattiske D.M., Pask A.J., Shaw J.M., Shaw G.; "Structure and expression of the follicle-stimulating hormone receptorgene in a marsupial, Macropus eugenii."; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20954 |
Swiss-prot Accession number | Q5D0K2 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 428 Amino acids |
Molecular weight | 47836 |
Domain Name | N/A |
References | 1 PubMed abstract 15765098 2 PubMed abstract 15765098 |
Hormone | N/A |
Gene ID | 488846 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20955 |
Swiss-prot Accession number | Q63931 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 430 Amino acids |
Molecular weight | 48211 |
Domain Name | N/A |
References | 1 PubMed abstract 7916580 2 PubMed abstract 7916580 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20956 |
Swiss-prot Accession number | O97772 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 427 Amino acids |
Molecular weight | 47387 |
Domain Name | N/A |
References | 1 PubMed abstract 7918628 2 PubMed abstract 7918628 |
Hormone | N/A |
Gene ID | 100009241 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20958 |
Swiss-prot Accession number | Q6VMN6 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. |
Protein Length | 370 Amino acids |
Molecular weight | 41251 |
Domain Name | N/A |
References | 1 PubMed abstract 14742914 2 PubMed abstract 16299503 3 PubMed abstract 14742914 4 PubMed abstract 16299503 |
Hormone | N/A |
Gene ID | 226278 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20971 |
Swiss-prot Accession number | O08786 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 436 Amino acids |
Molecular weight | 48437 |
Domain Name | N/A |
References | 1 PubMed abstract 9099891 2 PubMed abstract 9245702 3 PubMed abstract 16141072 4 PubMed abstract 15489334 5 PubMed abstract 9099891 6 PubMed abstract 9245702 7 PubMed abstract 16141072 8 PubMed abstract 15489334 |
Hormone | P09240 Detail in HMRbase |
Gene ID | 12425 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20976 |
Swiss-prot Accession number | O46600 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | Highly expressed in both adult and fetal liver. Lower levels in kidney, anterior pituitary, skeletal muscle, adipose tissue and mammary gland. |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 634 Amino acids |
Molecular weight | 70901 |
Domain Name | N/A |
References | 1 PubMed abstract 2289631 2 PubMed abstract 9710756 3 Zhou Y., Jiang H.; "Functional expression of bovine growth hormone receptor."; Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 11255006 5 PubMed abstract 10376317 |
Hormone | P01246 Detail in HMRbase |
Gene ID | 280805 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20980 |
Swiss-prot Accession number | P10912 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; single-pass type I membrane protein. GHBP: Secreted protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity). Isoform 2 remains fixed to the cell membrane and is not internalized. The proteolytic processed protein, GHBP, is secreted |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | Expressed in various tissues with high expression in liver and skeletal muscle. Isoform 4 is predominantly expressed in kidney, bladder, adrenal gland and brain stem. In the placenta, isoform 1 predominantly expressed in chorion and decidua, isoform 4 highly expressed in villi. Isoform 2 is expressed in lung, stomach and muscle. Low levels in liver. |
Post translational modification | The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. Shedding is inhibited by growth hormone (GH) binding to the receptor probably due to a conformational change in GHR rendering the receptor inaccessible to ADAM17 (By similarity). On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71500 |
Domain Name | N/A |
References | 1 PubMed abstract 2825030 2 PubMed abstract 2813379 3 PubMed abstract 1569971 4 PubMed abstract 8855247 5 PubMed abstract 9360546 6 PubMed abstract 9058373 7 Orlovsky I.V., Borovikova I.E., Rubtsov P.M.; "Comparing of nucleotide sequences of alternatively spliced region ofmammalian growth hormone receptor genes."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 8360189 9 PubMed abstract 10764769 10 PubMed abstract 2406245 11 PubMed abstract 11785980 12 PubMed abstract 2779634 13 PubMed abstract 8421103 14 PubMed abstract 8504296 15 PubMed abstract 8137822 16 PubMed abstract 7565946 17 PubMed abstract 9024232 18 PubMed abstract 9814495 19 PubMed abstract 9851797 20 PubMed abstract 10391209 21 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 22 PubMed abstract 10870033 23 PubMed abstract 14678285 24 PubMed abstract 1549776 25 PubMed abstract 8943276 |
Hormone | P01241 Detail in HMRbase |
Gene ID | 2690 |
PDB ID | 1A22 1AXI 1HWG 1HWH 1KF9 2AEW 3HHR |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20985 |
Swiss-prot Accession number | P16310 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway. Isoform 2 is mainly secreted. In adipose tissue, isoform 2 is mostly membrane associated |
Developmental Stage | Expression is low at birth. Increases to adult levels after 5 weeks. |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | Highest expression in liver. Also expressed in heart, kidney and muscle. |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2. Phosphorylation on either (or all of) Tyr-534, Tyr-566 and/or Tyr-627 is required for STAT5 activation. Phosphorylation on Tyr-333 would seem necessary for JAK2 activation. On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71237 |
Domain Name | N/A |
References | 1 PubMed abstract 2722883 2 PubMed abstract 2792761 3 PubMed abstract 1446642 4 PubMed abstract 8921876 5 PubMed abstract 8063815 6 PubMed abstract 7615519 7 PubMed abstract 10585430 8 PubMed abstract 7545168 9 PubMed abstract 9231797 |
Hormone | P01244 Detail in HMRbase |
Gene ID | 25235 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20989 |
Swiss-prot Accession number | P16882 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | During gestation, both hepatic and serum expression begins at day 9. Levels increased 8-fold in liver and 30-fold in serum by late gestation. Levels of isoform 1 and isoform 2 similarly begin at day 9 with isoform 1 expression reaching maximum levels by day 13, isoform 2 levels continue to increase until the end of pregnancy. |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | Expressed in all tissues tested including, liver, heart, adipose tissue, mammary gland, testes, ovary, brain, kidney and muscle. Highest levels in liver. |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 650 Amino acids |
Molecular weight | 72783 |
Domain Name | N/A |
References | 1 PubMed abstract 2739661 2 PubMed abstract 7988474 3 PubMed abstract 10425445 4 PubMed abstract 15489334 5 PubMed abstract 7894338 6 Zhou Y., He L., Kopchick J.J.; Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases. 7 Rowland J.E., Waters M.J.; "Mouse growth hormone receptor cytoplasmic exons 9 and 10 genomicclone with flanking intronic sequence."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 3398846 9 PubMed abstract 12379490 |
Hormone | P06880 Detail in HMRbase |
Gene ID | 14600 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20990 |
Swiss-prot Accession number | P19756 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71145 |
Domain Name | N/A |
References | 1 PubMed abstract 2243805 2 PubMed abstract 8647880 |
Hormone | P01248 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20991 |
Swiss-prot Accession number | P19941 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. Shedding is inhibited by growth hormone (GH) binding to the receptor probably due to a conformational change in GHR rendering the receptor inaccessible to ADAM17. On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization. |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71077 |
Domain Name | N/A |
References | 1 PubMed abstract 2825030 2 PubMed abstract 14519102 3 PubMed abstract 9878047 4 PubMed abstract 11108241 5 PubMed abstract 11418602 |
Hormone | P46407 Detail in HMRbase |
Gene ID | 100009325 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20992 |
Swiss-prot Accession number | P20395 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | Sertoli cells and ovarian granulosa cells. |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 692 Amino acids |
Molecular weight | 77681 |
Domain Name | N/A |
References | 1 PubMed abstract 2126341 2 PubMed abstract 1738373 3 PubMed abstract 7776966 4 PubMed abstract 2126341 5 PubMed abstract 1738373 6 PubMed abstract 7776966 |
Hormone | P11962 Detail in HMRbase P18427 Detail in HMRbase |
Gene ID | 25449 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20998 |
Swiss-prot Accession number | P23945 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | Sertoli cells and ovarian granulosa cells. |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 695 Amino acids |
Molecular weight | 78295 |
Domain Name | N/A |
References | 1 PubMed abstract 1709010 2 PubMed abstract 1301382 3 PubMed abstract 1322283 4 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15489334 6 PubMed abstract 1359889 7 PubMed abstract 7926278 8 PubMed abstract 7916967 9 PubMed abstract 8747461 10 PubMed abstract 15662415 11 PubMed abstract 7553856 12 PubMed abstract 9100567 13 PubMed abstract 9851774 14 PubMed abstract 9769327 15 PubMed abstract 10391209 16 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 17 PubMed abstract 12059813 18 PubMed abstract 11889179 19 PubMed abstract 12930927 20 PubMed abstract 12930928 21 PubMed abstract 1709010 22 PubMed abstract 1301382 23 PubMed abstract 1322283 24 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 25 PubMed abstract 15489334 26 PubMed abstract 1359889 27 PubMed abstract 7926278 28 PubMed abstract 7916967 29 PubMed abstract 8747461 30 PubMed abstract 15662415 31 PubMed abstract 7553856 32 PubMed abstract 9100567 33 PubMed abstract 9851774 34 PubMed abstract 9769327 35 PubMed abstract 10391209 36 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 37 PubMed abstract 12059813 38 PubMed abstract 11889179 39 PubMed abstract 12930927 40 PubMed abstract 12930928 41 PubMed abstract 1709010 42 PubMed abstract 1301382 43 PubMed abstract 1322283 44 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 45 PubMed abstract 15489334 46 PubMed abstract 1359889 47 PubMed abstract 7926278 48 PubMed abstract 7916967 49 PubMed abstract 8747461 50 PubMed abstract 15662415 51 PubMed abstract 7553856 52 PubMed abstract 9100567 53 PubMed abstract 9851774 54 PubMed abstract 9769327 55 PubMed abstract 10391209 56 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 57 PubMed abstract 12059813 58 PubMed abstract 11889179 59 PubMed abstract 12930927 60 PubMed abstract 12930928 |
Hormone | P01215 Detail in HMRbase P01225 Detail in HMRbase |
Gene ID | 2492 |
PDB ID | 1XUN 1XWD |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21004 |
Swiss-prot Accession number | P30551 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pancreas and brain. Also expressed in the gastrointestinal system and vagus nerve. |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 444 Amino acids |
Molecular weight | 49657 |
Domain Name | N/A |
References | 1 PubMed abstract 1313582 2 PubMed abstract 7654260 3 PubMed abstract 12916469 4 PubMed abstract 8024583 5 PubMed abstract 1313582 6 PubMed abstract 7654260 7 PubMed abstract 12916469 8 PubMed abstract 8024583 |
Hormone | P01355 Detail in HMRbase |
Gene ID | 24889 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21023 |
Swiss-prot Accession number | P32212 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 695 Amino acids |
Molecular weight | 78245 |
Domain Name | N/A |
References | 1 PubMed abstract 7504463 2 Gromoll J.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7504463 4 Gromoll J.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q6EV79 Detail in HMRbase Q9BEH3 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21026 |
Swiss-prot Accession number | P32238 (Sequence in FASTA format) |
Description | Cholecystokinin type A receptor (CCK-A receptor) (CCK-AR)(Cholecystokinin-1 receptor) (CCK1-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 428 Amino acids |
Molecular weight | 47841 |
Domain Name | N/A |
References | 1 PubMed abstract 8503909 2 PubMed abstract 8343165 3 PubMed abstract 7557108 4 PubMed abstract 10682840 5 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 10555959 8 PubMed abstract 11300760 9 PubMed abstract 8503909 10 PubMed abstract 8343165 11 PubMed abstract 7557108 12 PubMed abstract 10682840 13 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 14 PubMed abstract 15489334 15 PubMed abstract 10555959 16 PubMed abstract 11300760 |
Hormone | P06307 Detail in HMRbase |
Gene ID | 886 |
PDB ID | 1D6G 1HZN 1PB2 |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21039 |
Swiss-prot Accession number | P35376 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 695 Amino acids |
Molecular weight | 78085 |
Domain Name | N/A |
References | 1 PubMed abstract 7826612 2 PubMed abstract 7826612 |
Hormone | P01217 Detail in HMRbase P04837 Detail in HMRbase |
Gene ID | 281172 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21040 |
Swiss-prot Accession number | P35378 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 692 Amino acids |
Molecular weight | 77769 |
Domain Name | N/A |
References | 1 PubMed abstract 10330114 2 PubMed abstract 16141072 3 PubMed abstract 1459341 4 PubMed abstract 10330114 5 PubMed abstract 16141072 6 PubMed abstract 1459341 |
Hormone | P01216 Detail in HMRbase Q60687 Detail in HMRbase |
Gene ID | 14309 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21041 |
Swiss-prot Accession number | P35379 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Isoform FSH-R1: Cell membrane; multi-pass membrane protein. Isoform FSH-R2: Cell membrane; multi-pass membrane protein. Isoform FSH-R3: Cell surface |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | Isoform FSH-R3 is expressed in ovary and testis, but not in kidney. |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase. Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase. Isoform FSH-R3 may be involved in calcium signaling. |
Protein Length | 695 Amino acids |
Molecular weight | 78238 |
Domain Name | N/A |
References | 1 PubMed abstract 8394255 2 PubMed abstract 8439338 3 PubMed abstract 9364440 4 PubMed abstract 10527886 5 PubMed abstract 9364442 6 PubMed abstract 8394255 7 PubMed abstract 8439338 8 PubMed abstract 9364440 9 PubMed abstract 10527886 10 PubMed abstract 9364442 |
Hormone | P01218 Detail in HMRbase P01227 Detail in HMRbase |
Gene ID | 443299 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21043 |
Swiss-prot Accession number | P37125 (Sequence in FASTA format) |
Description | Chorionicgonadotropic hormone-like receptor (CGH-R) (Fragment). |
Source organism | Xanthomonas maltophilia (Pseudomonas maltophilia) (Stenotrophomonasmaltophilia) |
Taxonomical Classification | Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;Xanthomonadaceae; Stenotrophomonas. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 113 Amino acids |
Molecular weight | 12451 |
Domain Name | N/A |
References | 1 PubMed abstract 8427582 |
Hormone | P37126 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21046 |
Swiss-prot Accession number | P47799 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Among all mammalian FSH receptors, on the horse receptor does not bind LH/chorionic gonadotrophin (CG). |
Protein Length | 694 Amino acids |
Molecular weight | 78005 |
Domain Name | N/A |
References | 1 PubMed abstract 8198575 2 PubMed abstract 8198575 |
Hormone | P01220 Detail in HMRbase P01226 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21050 |
Swiss-prot Accession number | P49059 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 695 Amino acids |
Molecular weight | 78173 |
Domain Name | N/A |
References | 1 PubMed abstract 7590277 2 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7590277 4 Wang Y.F., Meyer K.B., Schmidt K., Wan S.J., Degen S.J.F.,la Barbera A.R.; "Porcine follicle-stimulating hormone receptor."; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01219 Detail in HMRbase P01228 Detail in HMRbase |
Gene ID | 397679 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21060 |
Swiss-prot Accession number | P79194 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 638 Amino acids |
Molecular weight | 71328 |
Domain Name | N/A |
References | 1 PubMed abstract 9228076 |
Hormone | P33093 Detail in HMRbase |
Gene ID | 697986 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21072 |
Swiss-prot Accession number | Q08501 (Sequence in FASTA format) |
Description | Prolactin receptor precursor (PRL-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; Single-pass type I membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for the anterior pituitary hormone prolactin. |
Protein Length | 608 Amino acids |
Molecular weight | 68241 |
Domain Name | N/A |
References | 1 PubMed abstract 8262385 2 PubMed abstract 8319571 3 Sasaki M.; Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases. 4 Edery M., Pezet A., Nandi S., Kelly P.A.; Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 2725531 |
Hormone | P04095 Detail in HMRbase P04768 Detail in HMRbase P06879 Detail in HMRbase P09586 Detail in HMRbase P18121 Detail in HMRbase P18918 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21081 |
Swiss-prot Accession number | Q28575 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 634 Amino acids |
Molecular weight | 70845 |
Domain Name | N/A |
References | 1 PubMed abstract 1980117 |
Hormone | P67930 Detail in HMRbase |
Gene ID | 443333 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21088 |
Swiss-prot Accession number | Q3UN81 (Sequence in FASTA format) |
Description | Adult male gall bladder cDNA, RIKEN full-length enriched library,clone:G630052A10 product:glucagon receptor, full insert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 485 Amino acids |
Molecular weight | 54871 |
Domain Name | N/A |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P55095 Detail in HMRbase |
Gene ID | 14527 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21103 |
Swiss-prot Accession number | Q5GJ04 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 695 Amino acids |
Molecular weight | 78829 |
Domain Name | N/A |
References | 1 Neubauer K., Fickel J., Jewgenow K.; "Cloning and sequencing of cat FSH receptor cDNA."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
2 Neubauer K., Fickel J., Jewgenow K.; "Cloning and sequencing of cat FSH receptor cDNA."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q52R91 Detail in HMRbase |
Gene ID | 554348 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21121 |
Swiss-prot Accession number | Q6R6L8 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 694 Amino acids |
Molecular weight | 78023 |
Domain Name | N/A |
References | 1 PubMed abstract 14749302 2 PubMed abstract 14749302 |
Hormone | Q9ERG5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21142 |
Swiss-prot Accession number | Q8HYN8 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in skin and adrenal gland tissues. |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 33283 |
Domain Name | N/A |
References | 1 PubMed abstract 12464015 2 PubMed abstract 12464015 |
Hormone | P01192 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21154 |
Swiss-prot Accession number | Q8R428 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity). |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 695 Amino acids |
Molecular weight | 77838 |
Domain Name | N/A |
References | 1 PubMed abstract 12506355 2 PubMed abstract 12506355 |
Hormone | Q9JK68 Detail in HMRbase Q9JK69 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21156 |
Swiss-prot Accession number | Q8SPZ1 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)(Fragment). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 59 Amino acids |
Molecular weight | 7090 |
Domain Name | N/A |
References | 1 Norgren R.B. Jr., Zink M.A., Jia Y., Ojeda S.R., Spindel E.R.; "Construction of a targeted rhesus macaque microarray."; Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | O97655 Detail in HMRbase P55247 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21167 |
Swiss-prot Accession number | Q95JF2 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Ailuropoda melanoleuca (Giant panda) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;Ailuropoda. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling (By similarity). |
Protein Length | 638 Amino acids |
Molecular weight | 70846 |
Domain Name | N/A |
References | 1 Liao M.J., Zhu M.Y., Zhang A.J.; "Molecular cloning of growth hormone receptor in giant panda."; Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | Q8HYE5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21169 |
Swiss-prot Accession number | Q95ML5 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Saimiri boliviensis boliviensis (Bolivian squirrel monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Saimiriinae; Saimiri. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. |
Protein Length | 632 Amino acids |
Molecular weight | 70884 |
Domain Name | N/A |
References | 1 PubMed abstract 11371582 |
Hormone | P58343 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21177 |
Swiss-prot Accession number | Q9BGN4 (Sequence in FASTA format) |
Description | Thyrotropin receptor precursor (TSH-R) (Thyroid-stimulating hormonereceptor). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 8 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5) (By similarity). |
Protein Length | 763 Amino acids |
Molecular weight | 86588 |
Domain Name | N/A |
References | 1 PubMed abstract 11796491 |
Hormone | Q52R90 Detail in HMRbase Q52R91 Detail in HMRbase |
Gene ID | 493842 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21191 |
Swiss-prot Accession number | Q9JI97 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | N/A |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling (By similarity). |
Protein Length | 628 Amino acids |
Molecular weight | 70355 |
Domain Name | N/A |
References | 1 PubMed abstract 12110920 2 PubMed abstract 10767558 3 Jullie H.A., Ymer S.I., Harrop S.A., Odorico D.M., Herington A.C.; "Sequence of the guinea pig growth hormone (GH) receptor: a possibleexplanation for the GH insensitivity of the guinea pig."; Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q9JKM4 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21192 |
Swiss-prot Accession number | Q9N1F8 (Sequence in FASTA format) |
Description | Pituitary growth hormone-releasing hormone receptor. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 423 Amino acids |
Molecular weight | 47435 |
Domain Name | N/A |
References | 1 PubMed abstract 12044609 |
Hormone | P63292 Detail in HMRbase Q9BDJ6 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21193 |
Swiss-prot Accession number | Q9NSD7 (Sequence in FASTA format) |
Description | Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptidereceptor 3) (Somatostatin- and angiotensin-like peptide receptor) (Gprotein-coupled receptor SALPR) (GPCR135). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis. |
Post translational modification | N/A |
Function | Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation. |
Protein Length | 469 Amino acids |
Molecular weight | 51124 |
Domain Name | N/A |
References | 1 PubMed abstract 10806363 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 14522968 4 PubMed abstract 15489334 |
Hormone | Q8WXF3 Detail in HMRbase |
Gene ID | 51289 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21200 |
Swiss-prot Accession number | Q9TU69 (Sequence in FASTA format) |
Description | Growth hormone receptor precursor (GH receptor) (Somatotropinreceptor) [Contains: Growth hormone-binding protein (GH-bindingprotein) (GHBP) (Serum-binding protein)]. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; single-pass type I membrane protein (By similarity). Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 1 fibronectin type-III domain. |
Tissue Specificity | Expressed in normal and tumorous mammary tissues, being localized in epithelial and myoepithelial/spindle cell components and in the activated fibroblasts of desmoplastic tumor stroma. Isoform 1, isoform 2 and isoform 3 are found in both normal and tumorous mammary tissues, isoform 1 being the predomiant isoform. Isoform 1, isoform 3, isoform 4 and isoform 5 are expressed in the CMT-U335 cell line. |
Post translational modification | On GH binding, phosphorylated on tyrosine residues in the cytoplasmic domain by JAK2 (By similarity). On ligand binding, ubiquitinated on lysine residues in the cytoplasmic domain. This ubiquitination is not sufficient for GHR internalization (By similarity). |
Function | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling (By similarity). |
Protein Length | 638 Amino acids |
Molecular weight | 71041 |
Domain Name | N/A |
References | 1 PubMed abstract 10579357 2 PubMed abstract 8894053 |
Hormone | P33711 Detail in HMRbase |
Gene ID | 403721 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21202 |
Swiss-prot Accession number | Q9YGN8 (Sequence in FASTA format) |
Description | Gonadotropin releasing hormone receptor type B. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 380 Amino acids |
Molecular weight | 42828 |
Domain Name | N/A |
References | 1 PubMed abstract 10051676 |
Hormone | O42471 Detail in HMRbase P51917 Detail in HMRbase P51924 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21203 |
Swiss-prot Accession number | Q9YGN9 (Sequence in FASTA format) |
Description | Gonadotropin releasing hormone receptor type A. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 40176 |
Domain Name | N/A |
References | 1 PubMed abstract 10051676 |
Hormone | O42471 Detail in HMRbase P51917 Detail in HMRbase P51924 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21557 |
Swiss-prot Accession number | Q5RLR7 (Sequence in FASTA format) |
Description | Nuclear receptor subfamily 4 group A member 2; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 40 Amino acids |
Molecular weight | 4642 |
Domain Name | N/A |
References | 1 PubMed abstract 16573537 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21655 |
Swiss-prot Accession number | Q9ARY7 (Sequence in FASTA format) |
Description | GABA-A receptor epsilon-like subunit (Putative uncharacterized protein) (Os01g0283300 protein) |
Source organism | Oryza sativa subsp. japonica (Rice) |
Taxonomical Classification | Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;Ehrhartoideae; Oryzeae; Oryza. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 273 Amino acids |
Molecular weight | 29550 |
Domain Name | N/A |
References | 1 PubMed abstract 15685292 2 PubMed abstract 16100779 3 PubMed abstract 16381971 4 PubMed abstract 17210932 5 PubMed abstract 12447438 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 4327905 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21716 |
Swiss-prot Accession number | O16754 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family protein 144, isoform a |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 64 Amino acids |
Molecular weight | 7610 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 186627 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21858 |
Swiss-prot Accession number | O55065 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Tokudaia osimensis osimensis (Ryukyu spiny rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Tokudaia. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 73 Amino acids |
Molecular weight | 7780 |
Domain Name | N/A |
References | 1 PubMed abstract 9657859 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21859 |
Swiss-prot Accession number | O55066 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Apodemus flavicollis (Yellow-necked field mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Apodemus; Sylvaemus group. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 73 Amino acids |
Molecular weight | 7799 |
Domain Name | N/A |
References | 1 PubMed abstract 9657859 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21910 |
Swiss-prot Accession number | O97607 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Monodelphis domestica (Short-tailed gray opossum) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 95 Amino acids |
Molecular weight | 10450 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21911 |
Swiss-prot Accession number | O97608 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Didelphis marsupialis virginiana (North American opossum) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Didelphis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 95 Amino acids |
Molecular weight | 10393 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21912 |
Swiss-prot Accession number | O97622 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Wallabia bicolor (Swamp wallaby) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Wallabia. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 95 Amino acids |
Molecular weight | 10304 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21913 |
Swiss-prot Accession number | O97667 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Macropus eugenii (Tammar wallaby) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Macropodidae; Macropus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 95 Amino acids |
Molecular weight | 10326 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21915 |
Swiss-prot Accession number | O97691 (Sequence in FASTA format) |
Description | Estrogen receptor beta; Fragment |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 79 Amino acids |
Molecular weight | 8879 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21935 |
Swiss-prot Accession number | P92158 (Sequence in FASTA format) |
Description | Retinoic acid receptor-beta isoform 2 (Retinoic acid receptor beta 2); Fragment |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 52 Amino acids |
Molecular weight | 5812 |
Domain Name | N/A |
References | 1 PubMed abstract 7703521 2 PubMed abstract 11073974 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21940 |
Swiss-prot Accession number | Q13262 (Sequence in FASTA format) |
Description | Oestrogen receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 44 Amino acids |
Molecular weight | 4604 |
Domain Name | N/A |
References | 1 PubMed abstract 8541239 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 21946 |
Swiss-prot Accession number | Q16095 (Sequence in FASTA format) |
Description | Estrogen receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 50 Amino acids |
Molecular weight | 5687 |
Domain Name | N/A |
References | 1 PubMed abstract 8275466 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21947 |
Swiss-prot Accession number | Q16405 (Sequence in FASTA format) |
Description | Estrogen receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 12 Amino acids |
Molecular weight | 1280 |
Domain Name | N/A |
References | 1 PubMed abstract 1779972 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22087 |
Swiss-prot Accession number | Q6CST7 (Sequence in FASTA format) |
Description | KLLA0C17985p |
Source organism | Kluyveromyces lactis (Yeast) (Candida sphaerica) |
Taxonomical Classification | Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 908 Amino acids |
Molecular weight | 95127 |
Domain Name | N/A |
References | 1 PubMed abstract 15229592 |
Hormone | N/A |
Gene ID | 2891929 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22195 |
Swiss-prot Accession number | Q6T928 (Sequence in FASTA format) |
Description | Vitamin D receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 29 Amino acids |
Molecular weight | 3339 |
Domain Name | N/A |
References | 1 PubMed abstract 16965356 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22253 |
Swiss-prot Accession number | Q7KX62 (Sequence in FASTA format) |
Description | Putative uncharacterized protein |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 161 Amino acids |
Molecular weight | 19119 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 3565324 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22319 |
Swiss-prot Accession number | Q800V1 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta; Fragment |
Source organism | Scyliorhinus canicula (Spotted dogfish) (Spotted catshark) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes;Scyliorhinidae; Scyliorhinus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 120 Amino acids |
Molecular weight | 13643 |
Domain Name | N/A |
References | 1 PubMed abstract 12200472 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22320 |
Swiss-prot Accession number | Q800V2 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha; Fragment |
Source organism | Scyliorhinus canicula (Spotted dogfish) (Spotted catshark) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes;Scyliorhinidae; Scyliorhinus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 120 Amino acids |
Molecular weight | 13701 |
Domain Name | N/A |
References | 1 PubMed abstract 12200472 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22330 |
Swiss-prot Accession number | Q80XG7 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Tympanoctomys barrerae (Plains viscacha rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Octodontidae; Tympanoctomys. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 48 Amino acids |
Molecular weight | 5602 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22338 |
Swiss-prot Accession number | Q863K5 (Sequence in FASTA format) |
Description | Vitamin D3 receptor; Fragment |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 132 Amino acids |
Molecular weight | 15166 |
Domain Name | N/A |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22371 |
Swiss-prot Accession number | Q86H24 (Sequence in FASTA format) |
Description | Thyroid hormone receptor; Fragment |
Source organism | Myxine glutinosa (Atlantic hagfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Hyperotreti; Myxiniformes;Myxinidae; Myxininae; Myxine. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 119 Amino acids |
Molecular weight | 13620 |
Domain Name | N/A |
References | 1 PubMed abstract 12200472 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22403 |
Swiss-prot Accession number | Q86S54 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family protein 58, isoform b |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 324 Amino acids |
Molecular weight | 37852 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 178573 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22543 |
Swiss-prot Accession number | Q8WNW9 (Sequence in FASTA format) |
Description | Estrogen receptor alpha; Fragment |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 12 Amino acids |
Molecular weight | 1301 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22551 |
Swiss-prot Accession number | Q8WY08 (Sequence in FASTA format) |
Description | Nuclear receptor NR5A2; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 21 Amino acids |
Molecular weight | 2230 |
Domain Name | N/A |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22604 |
Swiss-prot Accession number | Q91003 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta 2; Fragment |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 121 Amino acids |
Molecular weight | 14088 |
Domain Name | N/A |
References | 1 PubMed abstract 1576965 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22625 |
Swiss-prot Accession number | Q95J10 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 52 Amino acids |
Molecular weight | 6218 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22628 |
Swiss-prot Accession number | Q95J38 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 51 Amino acids |
Molecular weight | 5914 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22670 |
Swiss-prot Accession number | Q966B9 (Sequence in FASTA format) |
Description | Nuclear hormone receptor family protein 110, isoform a |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 326 Amino acids |
Molecular weight | 38154 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 178651 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22698 |
Swiss-prot Accession number | Q9BGG8 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha; Fragment |
Source organism | Sorex araneus (Eurasian common shrew) (European shrew) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Insectivora; Soricidae; Soricinae;Sorex. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 16 Amino acids |
Molecular weight | 1951 |
Domain Name | N/A |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22700 |
Swiss-prot Accession number | Q9BJK4 (Sequence in FASTA format) |
Description | Nuclear receptor NHR-98; Fragment |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 231 Amino acids |
Molecular weight | 26698 |
Domain Name | N/A |
References | 1 PubMed abstract 15983867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22701 |
Swiss-prot Accession number | Q9BJK6 (Sequence in FASTA format) |
Description | Nuclear receptor NHR-96; Fragment |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 253 Amino acids |
Molecular weight | 29408 |
Domain Name | N/A |
References | 1 PubMed abstract 15983867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22722 |
Swiss-prot Accession number | Q9DE17 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta4M'; Fragment |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 38 Amino acids |
Molecular weight | 4205 |
Domain Name | N/A |
References | 1 PubMed abstract 11073974 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22723 |
Swiss-prot Accession number | Q9DE18 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta4M; Fragment |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 39 Amino acids |
Molecular weight | 4276 |
Domain Name | N/A |
References | 1 PubMed abstract 11073974 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22724 |
Swiss-prot Accession number | Q9DE19 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta4'; Fragment |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 83 Amino acids |
Molecular weight | 9130 |
Domain Name | N/A |
References | 1 PubMed abstract 11073974 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22729 |
Swiss-prot Accession number | Q9DGR4 (Sequence in FASTA format) |
Description | SF-1; Fragment |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae;Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 206 Amino acids |
Molecular weight | 22947 |
Domain Name | N/A |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22733 |
Swiss-prot Accession number | Q9ES42 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta 3; Fragment |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 32 Amino acids |
Molecular weight | 3696 |
Domain Name | N/A |
References | 1 PubMed abstract 11046130 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22735 |
Swiss-prot Accession number | Q9GKJ1 (Sequence in FASTA format) |
Description | Retinoic acid receptor beta; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 42 Amino acids |
Molecular weight | 4972 |
Domain Name | N/A |
References | 1 PubMed abstract 11528129 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22745 |
Swiss-prot Accession number | Q9GTC4 (Sequence in FASTA format) |
Description | Nuclear receptor NHR-95; Fragment |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 470 Amino acids |
Molecular weight | 55123 |
Domain Name | N/A |
References | 1 PubMed abstract 15983867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22769 |
Swiss-prot Accession number | Q9GTF5 (Sequence in FASTA format) |
Description | Nuclear receptor NHR-57; Fragment |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 48 Amino acids |
Molecular weight | 5698 |
Domain Name | N/A |
References | 1 PubMed abstract 15983867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22785 |
Swiss-prot Accession number | Q9H1Z6 (Sequence in FASTA format) |
Description | Estrogen receptor 1; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 12 Amino acids |
Molecular weight | 1385 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22813 |
Swiss-prot Accession number | Q9JM97 (Sequence in FASTA format) |
Description | Estrogen receptor beta; Fragment |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 139 Amino acids |
Molecular weight | 15215 |
Domain Name | N/A |
References | 1 PubMed abstract 11418189 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22815 |
Swiss-prot Accession number | Q9MZS0 (Sequence in FASTA format) |
Description | Steroidogenic factor-1; Fragment |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 181 Amino acids |
Molecular weight | 19313 |
Domain Name | N/A |
References | 1 PubMed abstract 11108279 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22824 |
Swiss-prot Accession number | Q9N418 (Sequence in FASTA format) |
Description | Putative uncharacterized protein |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 206 Amino acids |
Molecular weight | 23094 |
Domain Name | N/A |
References | 1 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 189677 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22856 |
Swiss-prot Accession number | Q9QVT1 (Sequence in FASTA format) |
Description | Retinoic acid receptor ALPHAM403, RARALPHAM403; Fragment |
Source organism | Mus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 42 Amino acids |
Molecular weight | 4775 |
Domain Name | N/A |
References | 1 PubMed abstract 7891690 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22857 |
Swiss-prot Accession number | Q9QVT2 (Sequence in FASTA format) |
Description | Retinoic acid RECEPTORGAMMABM396, RARGAMMABM396 |
Source organism | Mus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 35 Amino acids |
Molecular weight | 3998 |
Domain Name | N/A |
References | 1 PubMed abstract 7891690 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22858 |
Swiss-prot Accession number | Q9QVT3 (Sequence in FASTA format) |
Description | Retinoic acid RECEPTORGAMMABM382, RARGAMMABM382 |
Source organism | Mus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 21 Amino acids |
Molecular weight | 2430 |
Domain Name | N/A |
References | 1 PubMed abstract 7891690 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22864 |
Swiss-prot Accession number | Q9QW39 (Sequence in FASTA format) |
Description | Estrogen receptor; Fragment |
Source organism | Rattus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus; unclassified Rattus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 51 Amino acids |
Molecular weight | 5846 |
Domain Name | N/A |
References | 1 PubMed abstract 1473557 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22901 |
Swiss-prot Accession number | Q9UD41 (Sequence in FASTA format) |
Description | Beta-isoform thyroid hormone receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 16 Amino acids |
Molecular weight | 1920 |
Domain Name | N/A |
References | 1 PubMed abstract 7528740 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22905 |
Swiss-prot Accession number | Q9UKJ6 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 9 Amino acids |
Molecular weight | 1272 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22918 |
Swiss-prot Accession number | Q9XS80 (Sequence in FASTA format) |
Description | Androgen receptor; Fragment |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 31 Amino acids |
Molecular weight | 3733 |
Domain Name | N/A |
References | ---- |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22919 |
Swiss-prot Accession number | Q9XSB2 (Sequence in FASTA format) |
Description | Thyroid hormone receptor alpha2; Fragment |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 60 Amino acids |
Molecular weight | 6522 |
Domain Name | N/A |
References | 1 PubMed abstract 10407478 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22920 |
Swiss-prot Accession number | Q9XSB3 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta1; Fragment |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 62 Amino acids |
Molecular weight | 7111 |
Domain Name | N/A |
References | 1 PubMed abstract 10407478 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22921 |
Swiss-prot Accession number | Q9XSB4 (Sequence in FASTA format) |
Description | Thyroid hormone receptor beta2; Fragment |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 45 Amino acids |
Molecular weight | 5045 |
Domain Name | N/A |
References | 1 PubMed abstract 10407478 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22947 |
Swiss-prot Accession number | Q9Y2W8 (Sequence in FASTA format) |
Description | Alternatively-spliced estrogen receptor alpha; Fragment |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 113 Amino acids |
Molecular weight | 12635 |
Domain Name | N/A |
References | ---- |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22965 |
Swiss-prot Accession number | Q8SWL9 (Sequence in FASTA format) |
Description | Similarity to LEPTIN RECEPTOR GENE-RELATED PROTEIN |
Source organism | Encephalitozoon cuniculi |
Taxonomical Classification | Eukaryota; Fungi; Microsporidia; Unikaryonidae; Encephalitozoon. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 102 Amino acids |
Molecular weight | 12130 |
Domain Name | N/A |
References | 1 PubMed abstract 11719806 2 PubMed abstract 11157783 |
Hormone | N/A |
Gene ID | 860248 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |