NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a
CompoundNaringenin
NPACT-IdNPACT00798
IUPAC5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
Synonymsnaringenin ;Naringenine;(-)-Naringenin;NARIGENIN;(S)-Naringenin;naringetol;salipurpol;Salipurol
PubChem Id932
ClassFlavonoid
In-vitro anticancer activity 19 cancer cell lines
In-Vivo anticancer activity Yes
TargetsBAX | BCL2L1 | CASP3 | CCNB1 | CDC25C | CDK1 | COX-1 | CYP19A1 | CYPIA1 | NOS2 | NQO1 | PARP1 |   All | 
Properties Physical   Elemental  Topological
InChi KeyFTVWIRXFELQLPI-UHFFFAOYSA-N
InChi1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
SMILESO1[C@H](CC(=O)c2c1cc(O)cc2O)c1ccc(O)cc1
SMART[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC2=C([H])C(O[H])=C([H])C(O[H])=C2C(=O)C1([H])[H]
CAS No.480-41-1
Structure
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Cross Refrence in other databases
Super Natural   000480411
CTD   C005273
HIT   C0352
NCI-60 GI50 data   -
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Drug-Likeliness Filters Lipinski's rule of five   Yes
Ghose filter   Yes
Veber filter   Yes
Muegge Filter   Yes
Similarity SearchHuman metabolite databaseFDA approved drugs

 






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