Compound	Silvestrol
NPACT-Id	NPACT00946
IUPAC	methyl D824(1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Synonyms	-
PubChem Id	11787114
Class	Terpenoids
In-vitro anticancer activity	3 cancer cell lines
In-Vivo anticancer activity	Yes
Targets	BCL2 \| birc5a \| CCND1 \| MCL1 \| MYC \| All \|
Properties	Physical Elemental Topological
InChi Key	GVKXFVCXBFGBCD-QKDMMWSPSA-N
InChi	1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-32)22(36)16-35/h5-15,22,25-27,29,31-32,35-37,39H,16-17H2,1-4H3/t22-,25-,26-,27-,29-,31-,32-,33+,34+/m1/s1
SMILES	O1[C@@]2([C@@](O)([C@H](O)[C@@H]([C@H]2c2ccccc2)C(=O)OC)c2c1cc(O[C@@H]1O[C@H](CO[C@H]1OC)[C@H](O)CO)cc2OC)c1ccc(OC)cc1
SMART	[H]OC([H])([H])[C@@]([H])(O[H])[C@]1([H])O[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C3C(O[C@@]4(C5=C([H])C([H])=C(OC([H])([H])[H])C([H])=C5[H])[C@]([H])(C5=C([H])C([H])=C([H])C([H])=C5[H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(O[H])[C@@]34O[H])=C2[H])[C@]([H])(OC([H])([H])[H])OC1([H])[H]
CAS No.	-
Structure Download
Cross Refrence in other databases
	Super Natural	-
	CTD	C489897
	HIT	-
	NCI-60 GI₅₀ data	-
Suppliers	NA,
Drug-Likeliness Filters	Lipinski's rule of five	No
	Ghose filter	No
	Veber filter	No
	Muegge Filter	No
Similarity Search	Human metabolite database	FDA approved drugs

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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