NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

a

Compound: 6-shogaol

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

PLAU

plasminogen activator, urokinase

5328

Hepatoma

Hep-3B

-

-

-

-

The physiological activity of MMP-9 is significantly related to the activity of uPA and TIMPs. uPA activity was not detectable in HepG2 cells with or without PMA induction, but it dose-dependently decreased in Hep3B cells after incubation with 6-shogaol for 24 h.

20521273

PLAU

plasminogen activator, urokinase

5328

Hepatoma

Hep G2

-

-

-

-

The physiological activity of MMP-9 is significantly related to the activity of uPA and TIMPs. uPA activity was not detectable in HepG2 cells with or without PMA induction, but it dose-dependently decreased in Hep3B cells after incubation with 6-shogaol for 24 h.

20521273

Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.