NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Alpha-Curcumene

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

caspase 3, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

-

-

-

-

Alpha-Curcumene activated caspases 3 after 3 h

caspase 7, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

-

-

-

-

Alpha-Curcumene activated caspases 7 after 3 h

caspase 8, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

-

-

-

-

Alpha-Curcumene activated caspases 8 after 1 h

caspase 9, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

-

-

-

-

Alpha-Curcumene activated caspases caspases 9 after 12 h

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.