NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Biochanin A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Prostate CancerLNCaP----The study proved that one of anti-prostate cancer mechanisms by biochanin-A through increase of p21 pathway resulted in decreased PLK-1 expression as a consequence of apoptotic cell death.22065906
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Prostate CancerPC-3----The study proved that one of anti-prostate cancer mechanisms by biochanin-A through increase of p21 pathway resulted in decreased PLK-1 expression as a consequence of apoptotic cell death.22065906
PLK1polo-like kinase 15347Prostate CancerLNCaP----The study proved that one of anti-prostate cancer mechanisms by biochanin-A through increase of p21 pathway resulted in decreased PLK-1 expression as a consequence of apoptotic cell death.22065906
PLK1polo-like kinase 15347Prostate CancerPC-3----The study proved that one of anti-prostate cancer mechanisms by biochanin-A through increase of p21 pathway resulted in decreased PLK-1 expression as a consequence of apoptotic cell death.22065906

 






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