NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Butein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CHUKconserved helix-loop-helix ubiquitous kinase1147Prostate CancerLNCaP----IKKalpha protein level was measured to evaluate the possible inhibitory mechanism of butein on IkBalpha protein degradation. Immunoblot analysis showed that pretreatment of LNCaP cells with butein inhibited IKKa in a dose-dependent manner.22114764

 






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