NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Cucurbitacin I

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)6774Lung adenocarcinomaA5490.8±0.7 µM---Cucurbitacin I treatment suppressed P-STAT3.15735720
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)6774Breast CarcinomaMDA-MB-4354.6±1.9 µM---Cucurbitacin I treatment suppressed P-STAT3.15735720
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)6774Breast CarcinomaMDA-MB-4687.5±1.5 µM---Cucurbitacin I treatment suppressed P-STAT3.15735720

 






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