NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Deguelin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AKT1v-akt murine thymoma viral oncogene homolog 1207Human promyelocytic leukemiaHL-60----P-Akt protein level in HL-60 cells was reduced after 24-48 h treatment with deguelin at the concentrations of 20.14 nM. This indicates that deguelin promotes P-Akt protein degradation in HL-60 cells in a time-dependent manner.19455392

 






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