NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Deguelin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Adult T-cell leukemia (ATL) KUT-1----Caspase-3 was cleaved after treatment of KUT-1 cells with deguelin for at least 24 h, suggesting that deguelin induces cell death of these cells, at least in part via the apoptosis pathway involving caspase-3.19781773
CASP3caspase 3, apoptosis-related cysteine peptidase836Adult T-cell leukemia (ATL) MT-2----Caspase-3 was cleaved after treatment of MT-2 cells with deguelin for at least 24 h, suggesting that deguelin induces cell death of these cells, at least in part via the apoptosis pathway involving caspase-3.19781773

 






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