NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Eupatorin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CYP1A1cytochrome P4501543Breast CarcinomaMDA-MB-468----Eupatorin was shown to arrest the cell cycle of the CYP1-expressing cell line MDA-MB-468 in G2/M phase. It strongly inhibits proliferation of MDA-MB-468 cells at submicromolar concentrations as a result of CYP1A1 enzyme metabolism.18454852
CYP1B1cytochrome P450, family 1, subfamily B, polypeptide 11545Breast CarcinomaMDA-MB-468----Eupatorin was shown to arrest the cell cycle of the CYP1-expressing cell line MDA-MB-468 in G2/M phase. It strongly inhibits proliferation of MDA-MB-468 cells at submicromolar concentrations as a result of CYP1B1 enzyme metabolism.18454852

 






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