NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: falcarindiol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
TP53tumor protein p537157Breast adenocarcinomaMCF-7----Falcarindiol was found to have anti-proliferative effect against MCF-7 human breast cancer cells by induction of a G0/G1 cell cycle block of the cells, with an IC50 value of 35.67 µM.falcarindiol induced apoptosis through strongly increased mRNA expression of p53 in a dose dependent manner.22019572

 






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