NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Fisetin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDK4cyclin-dependent kinase 41019Colon CancerHT-29----CDK4 activity was drastically decreased within 30 min of Fisetin treatment, which was consistently lower in Fisetin-treated cells throughout the 12-h incubation period (P< 0.05).Fisetin also inhibited CDk4 activity in a cell-free system (P < 0.05), indicating that it may directly inhibit CDk4 activity.16317137

 






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