NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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a

Compound: Gallic acid

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Gastric Cancer

AGS

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MMP-2 activity was markedly reduced with GA. The inhibitory effects were more significant at concentrations of 2.5 and 3.5µM.GA presents a strong suppression on AGS cell growth and MMP secretion. GA possesses almost 600 times higher suppressive effect on MMP secretion than Caffic acid and Protocatechuic acid.

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