NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Glabridin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
PTK2PTK2 protein tyrosine kinase 25747Breast CarcinomaMDA-MB-231----FAK is essential for the regulation of integrin-mediated cell adhesion and migration of cancer cells. Glabridin decreased the phosphorylation of FAK at Tyr 397, 576 and 925 sites in both MDA-MB-231 cells.20626003

 






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