NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Limonin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BAXBCL2-associated X protein581Colon CancerSW-480----Expression of Bax was 3.0 and 5.0-fold higher with limonin (100 µM) treatment for 24 and 48 h, respectively, compared to control. The ratio of Bcl2 to Bax was significantly lower (up to 9-fold), after 48 h of incubation with limonin.21338095

 






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