NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Luteolin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)4318Epidermal CarcinomaA431-III----Cells were treated with different concentrations(10-40 µM) of Luteolin for 24 h. The results showed that treatment with Luteolin dose-dependently decreased MMP-9 activity in the conditioned medium in A431-III cells.21752154
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)4318Epidermal CarcinomaA431-P----Cells were treated with different concentrations(10-40 µM) of Luteolin for 24 h. The results showed that treatment with Luteolin dose-dependently decreased MMP-9 activity in the conditioned medium.21752154

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.