NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Lycorine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NOS2nitric oxide synthase 2, inducible4843Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRaw2641.2±0.4 µM---TNF-a suppressive alkaloids also inhibited NO production in RAW264 cell.21372424
TNFtumor necrosis factor7124Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRaw2642.1±0.4 µM---Lycorine suppressed the TNF-a production in LPS-stimulated RAW264 cells21372424

 






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