NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Morusin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP8caspase 8, apoptosis-related cysteine peptidase841Colon CancerHT-29----Morusin, activate caspase-8 to elevate mitochondrial tBid and Bax to permeabilize the outer mitochondrial membrane, allowing eflux of cytochrome c and Smac/DIABLO into cytosol.18485277

 






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