NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
a

Compound: Mucronulatol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Colorectal AdenocarcinomaHCT-8----Increasing concentrations of mucronulatol induced an up-regulation of both p21Cip1 protein level.Increment in p21Cip1/p27Kip1 protein levels, inhibiting the physiological functions of the cyclin E/CDK2 complex.18538108

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.