NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Mucronulatol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)1027Colorectal AdenocarcinomaHCT-8----Increasing concentrations of mucronulatol induced an up-regulation of both p27kip1 protein level.Increment in p21Cip1/p27Kip1 protein levels, inhibiting the physiological functions of the cyclin E/CDK2 complex.18538108

 






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