NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Mucronulatol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
TOP2Atopoisomerase (DNA) II alpha 170kDa7153Colorectal AdenocarcinomaHCT-8----We observed a presumptive compensatory effect in the expression of topoisomerase II-alpha, which is up-regulated.It appears that the gene expression of topoisomerase II-alpha remained unaltered, whereas its protein levels suffered an increase in a drug concentration-dependent manne.18538108

 






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