NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Osthole

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Lung adenocarcinomaA549----Results indicated that Osthole up-regulation of the Bax/Bcl-2 ratio in a dose-dependent manner.21447176
CCNB1cyclin B1891Lung adenocarcinomaA549----Western blotting analysis revealed that Osthole decreased the protein levels of Cyclin B1 via a dose-dependent manner.21447176
CDK1cyclin-dependent kinase 1983Lung adenocarcinomaA549----Western blotting analysis revealed that Osthole decreased the protein levels of p-Cdc2 via a dose-dependent manner.21447176

 






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