NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Pinocembrin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Colon cancerHCT-116----The processing of caspase-3 was evident from 24 h of pinocembrin treatment and by 48 hmore intense cleavage fragment was evident. Caspase-3 inhibitor reduced the chromatin condensation to 15%, compared to 30% in DMSO control.17186548

 






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