NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Taxifolin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NQO1NAD(P)H dehydrogenase, quinone 11728Colon cancerHCT-116----Taxifolin induced a moderate increase in QR activity at a concentration range of 31.3 to 62.5 mM, while QR activity was decreased at higher concenrations (125—250 mM) due to cytotoxicity.It was cytotoxic to HCT116 cell lines, with an IC50 value of 63.42.The CD of taxifolin was 11.03 mM, leading to a CI value of 5.7.17541156

 






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