NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Tomatidine

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NOS2nitric oxide synthase 2, inducible4843Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.7----The iNOS protein was barely detectable in unstimulated cells but markedly increased after LPS treatment, and tomatidine caused dose-dependent inhibition of LPS-induced iNOS expression.18544347

 






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