NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Alpha-Naphthoflavone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AHRaryl hydrocarbon receptor196Breast adenocarcinomaMCF-7----Alpha-naphtoflavone caused a concentration-dependent decrease in the levels of this nuclear Ah receptor complex.8390116
CYP1A1cytochrome P4501543Breast adenocarcinomaMCF-7----Cotreatment of the cells with 10-9 M TCDD and differential concentrations of alpha-naphthaflavone (10-8, 10-7, or 10-6 M) resulted in a concentration dependent decrease in CYP1A1 mRNA levels8390116

 






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