NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase
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Compound: Magnolol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Colon CancerCOLO-205----Magnolol dose-dependently increases p21 level in COLO-205 cells. Results suggested that cell membrane associated inositol trisphosphate signaling pathway was involved in the magnolol-induced elevation of [Ca2]and increase of p21 protein level.11813258
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026HepatomaHep G2----Magnolol dose-dependently increases p21 level in Hep-G2. Results suggested that cell membrane associated inositol trisphosphate signaling pathway was involved in the magnolol-induced elevation of [Ca2]and increase of p21 protein level.11813258

 






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