NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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a

Compound: 2-alpha, 3-alpha, 19-beta, 23-beta-tetrahydroxyurs-12-en-28-oic acid

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

caspase 8, apoptosis-related cysteine peptidase

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A2780

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Consistent with its effect on apoptosis,THA induced changes in the expression of apoptosis related proteins in A2780. The expression of procaspase-8 was clearly decreased in a dose-dependent manner.

caspase 8, apoptosis-related cysteine peptidase

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HepG2

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Consistent with its effect on apoptosis,THA induced changes in the expression of apoptosis related proteins in HepG2. The expression of procaspase-8 was clearly decreased in a dose-dependent manner.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.