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The total number entries retrieved from this search areID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
---|---|---|---|---|---|---|---|
1345 | pGlu-EDSG | Epidermal pentapeptide | It induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher doses | Colcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test. | Significant mitotic rate inhibition initially and on day 7 after an overshoot on day 6 | Back skin of female hairless mice (hr/hr) | 1977237 |
1346 | pGlu-EDSG | Epidermal pentapeptide | It induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher doses | Colcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test. | Initial increase in mitotic rate, peaking on day 2, from day 2 to day 10, mitotic rate was lower than normal. | Back skin of female hairless mice (hr/hr) | 1977237 |
1347 | pGlu-EDSG | Epidermal pentapeptide | It induces a moderate but long-lasting inhibition of epidermal cell proliferation when given at low (picomol) doses but stimulates epidermal cell proliferation at higher doses | Colcemid-arrested mitoses and labelled cells were counted per 12 mm of interfollicular epidermis in 5 pm paraffin sections stationed with haematoxylin in the former and dipcoated with NTB 2 emulsion and incubated for 3 weeks at 0-4 ͦC for later. The statistical evaluations were made according to the Wilcoxon's rank sum test. | The mitotic rate was strongly increased with peaks at days 1, 3 and 6 (twice the control value). | Back skin of female hairless mice (hr/hr) | 1977237 |