Peptide Analogs

This module allow users to predict immunomodulatory activity of their peptide. In addition, this module generates all possible analogs of a given peptide (all possible single mutations) and predicts immunomodulatory activity of each mutant along with all the important physicochemical properties (like hydrophobicity, charge, pI). As a possible application, user can identify and alter a particular residue, which can reduce/increase the immunomodulatory potency of a peptide drastically. In summary this module help to design vaccine ajuvants using analog-based approach.

Peptide Submission Form

Paste/Type Peptide Sequence:


Select model for prediction:     Please select prediction method, SVM-based or SVM+motif-based, if you need motif information for prediction.

 Dipeptide Composition  

Dipeptide Composition + Motif  

Choose SVM threshold:

0.0 -1.0 -0.9 -0.8 -0.7 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0     SVM threshold is required for prediction. Moving the threshold value
in either direction (+1 or -1) will lead to increase
in probability of correct prediction in that direction.

Optional (Peptide Property)

This server allow users to compute physicochemical property of residues. Please select property you wish to calculate

  Hydrophobicity

  Steric hinderance

  Solvation

   Amphiphilicity

  Net Hydrogen

   Charge

   pI

   Molecular weight

All