HIP1129 details

HIPidHIP1129
SequenceRQLLSGIVQQQNNLLRAIEAQQHLLQK
Length27
NomenclatureN27
Sourcegp41
Cell line TZM-bl
Inhibition/IC50  338
Unit nM
TargetFusion inhibitor
AssayLuciferase assay
PropertiesView
StructureJmol
PaperVirus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain.
AuthorsWexler-Cohen Y, Ashkenazi A, Viard M, Blumenthal R, Shai Y.
ReferenceFASEB J. 2010 Nov;24(11):4196-202. Epub 2010 Jul 6.
Pubmed ID20605950

 CSIR-Institute of Microbial Technology, Chandigarh 160036, India