| |
HIPid | HIP1129 |
Sequence | RQLLSGIVQQQNNLLRAIEAQQHLLQK |
Length | 27 |
Nomenclature | N27 |
Source | gp41 |
Cell line | TZM-bl |
Inhibition/IC50 | 338 |
Unit |
nM |
Target | Fusion inhibitor |
Assay | Luciferase assay |
Properties | View |
Structure | Jmol |
Paper | Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain. |
Authors | Wexler-Cohen Y, Ashkenazi A, Viard M, Blumenthal R, Shai Y. |
Reference | FASEB J. 2010 Nov;24(11):4196-202. Epub 2010 Jul 6. |
Pubmed ID | 20605950 |