Database of HIV inhibiting peptides
| HIPid | HIP215 |
| Sequence | TYICEVEDQKEE |
| Length | 12 |
| Nomenclature | CD4 (81-92) |
| Source | V1J1 region of the CD4 molecule |
| Cell line | CEM-SS |
| Inhibition/IC50 | >500 |
| Unit | μM |
| Target | Fusion inhibitor |
| Assay | Cytopathic effect |
| Properties | View |
| Structure | Jmol |
| Paper | Peptides derived from the CDR3-homologous domain of the CD4 molecule are specific inhibitors of HIV-1 and SIV infection, virus-induced cell fusion, and postinfection viral transmission in vitro. Implications for the design of small peptide anti-HIV therapeutic agents. |
| Authors | Rausch DM, Hwang KM, Padgett M, Voltz AH, Rivas A, Engleman E, Gaston I, McGrath M, Fraser B, Kalyanaraman VS, et al. |
| Reference | Ann N Y Acad Sci. 1990;616:125-48. Review. |
| Pubmed ID | 2078014 |
CSIR-Institute of Microbial Technology, Chandigarh 160036, India