HIP518 details

HIPidHIP518
SequenceRGTKALTEVIPLTEEAEC
Length18
NomenclaturePepA
SourcePep-A/Synthetic
Cell line HeLa
Inhibition/IC50  35±5
Unit (Ki)μM
TargetReverse Transcriptase
AssayRT-Polymerase Assay
PropertiesView
StructureJmol
PaperA new generation of peptide-based inhibitors targeting HIV-1 reverse transcriptase conformational flexibility.
AuthorsAgopian A, Gros E, Aldrian-Herrada G, Bosquet N, Clayette P, Divita G.
ReferenceJ Biol Chem. 2009 Jan 2;284(1):254-64. Epub 2008 Oct 23.
Pubmed ID18952602

 CSIR-Institute of Microbial Technology, Chandigarh 160036, India