HIPid | HIP945 |
Sequence | WEEWDKKIEEYTKKIEELIKKSEEQQKN |
Length | 28 |
Nomenclature | SC29EK |
Source | gp41 |
Cell line | HeLa CD4 |
Inhibition/IC50 | 2.4±0.1 |
Unit | nM |
Target | Replication |
Assay | MAGI assay |
Properties | View |
Structure | Jmol |
Paper | SC29EK, a peptide fusion inhibitor with enhanced alpha-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide. |
Authors | Naito T, Izumi K, Kodama E, Sakagami Y, Kajiwara K, Nishikawa H, Watanabe K, Sarafianos SG, Oishi S, Fujii N, Matsuoka M. |
Reference | Antimicrob Agents Chemother. 2009 Mar;53(3):1013-8. Epub 2008 Dec 29. |
Pubmed ID | 19114674 |