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This page gives details of CPPsite entry with ID 1024
Primary information
CPPsite ID1024
PEPTIDE SEQUENCEGRKKRRQRPPQC
PEPTIDE NAMEArg deletion mutant of Tat (48-60)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONNucleus and nucleolus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein
UPTAKE EFFICIENCYLow (25 % relative to Tat (48-60))
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (fluorescein)
PMID0
PATENTUnknown
LENGTH12
Secondary StructureCCCCCSSCCSCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C=O
Tertiary Structure
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  (PEPstrMOD)