This page gives details of CPPsite entry with ID 1025 |
Primary information | |
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CPPsite ID | 1025 |
PEPTIDE SEQUENCE | GRKKRRQPPQC |
PEPTIDE NAME | Arg deletion mutant of Tat (48-60) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Nucleus and nucleolus |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Conjugation with fluorescein |
UPTAKE EFFICIENCY | Low (10 % relative to Tat (48-60)) |
PROPOSED UPTAKE MECHANISM | Probably non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa |
CARGO | Fluorophore (fluorescein) |
PMID | 0 |
PATENT | Unknown |
LENGTH | 11 |
Secondary Structure | CCCSSSCCCCC |
SMILES | NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |