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This page gives details of CPPsite entry with ID 1054
Primary information
CPPsite ID1054
PEPTIDE SEQUENCELNSAGYLLGKLKALAALAKIL
PEPTIDE NAMETP12
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEChimeric
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm and nucleus and intracellular membranous structures
N-TERMINAL MODIFICATIONBiotinylation at amino group of Lys
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower than Transportan
PROPOSED UPTAKE MECHANISMProbably non-receptor mediated endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHuman bowes melanoma cells
CARGOBiotin
PMID10930519
PATENTUnknown
LENGTH21
Secondary StructureCTTTTTSTTTTHHHHTTTTTC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C=O
Tertiary Structure
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