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This page gives details of CPPsite entry with ID 1134
Primary information
CPPsite ID1134
PEPTIDE SEQUENCERQIKIFFQNRRMKFKK
PEPTIDE NAMEPen2W2F
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUneven distribution of peptide with accumulation in centrosmal area and in
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh and comparable to (pAntp) (43-58)
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEPC-12 and V79 cells
CARGOFluorophore (fluorescein)
PMID12849987
PATENTUnknown
LENGTH16
Secondary StructureCCHHHHHHHHHTTTTC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCC[NH3])CCCC[NH3])Cc1ccccc1)CCCC[NH3])CCSC)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1ccccc1)[C@H](CC)C)CCCC[NH3])[C@H](CC)C)CCC(=O)N)CCCNC(=[NH2])N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Experimentally determined structure from PDB)