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This page gives details of CPPsite entry with ID 1135
Primary information
CPPsite ID1135
PEPTIDE SEQUENCERQIRIWFQNRRMRWRR
PEPTIDE NAMEPenArg
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONUneven distribution of peptide with accumulation in centrosmal area and in
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh and comparable to (pAntp) (43-58)
PROPOSED UPTAKE MECHANISMEnergy-independent endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEPC-12 and V79 cells
CARGOFluorophore (fluorescein)
PMID12849987
PATENTUnknown
LENGTH16
Secondary StructureCCSSSCSSSCCSSSCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)