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This page gives details of CPPsite entry with ID 1216
Primary information
CPPsite ID1216
PEPTIDE SEQUENCEGRKKRRQRRRPPQ
PEPTIDE NAMETat (48-60)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONCys addition
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYUnknown
PROPOSED UPTAKE MECHANISMEnergy-dependent endocytic process involving cell membrane lipid rafts
INVITRO/INVIVOIn vitro
CELL LINEHeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures
CARGOProtein (PO and IgG)
PMID15859953
PATENTUS 20040132970
LENGTH13
Secondary StructureCCTTSCCSSCSCC
SMILESNCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)