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This page gives details of CPPsite entry with ID 1306
Primary information
CPPsite ID1306
PEPTIDE SEQUENCELLIILRRRIARKQAHAHSK
PEPTIDE NAMEpVEC mutant
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYProbably Amphipathic
SUB CELLULAR LOCALIZATIONPrabably cytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYComparable to pVEC
PROPOSED UPTAKE MECHANISMProbably receptor independent endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHuman bowes melanoma cells
CARGOFluorophore (fluorescein)
PMID16808894
PATENTUnknown
LENGTH19
Secondary StructureCCSSCHHHHHHHHTTTTCC
SMILESN[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCC[NH3])C=O
Tertiary Structure
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  (PEPstrMOD)