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This page gives details of CPPsite entry with ID 1400 |
| Primary information | |
|---|---|
| CPPsite ID | 1400 |
| PEPTIDE SEQUENCE | NAKTRRHERRRKLAIERGC |
| PEPTIDE NAME | P22 N |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Protein derived |
| CATEGORY | Cationic |
| SUB CELLULAR LOCALIZATION | Cytoplasm and nucleus |
| N-TERMINAL MODIFICATION | Free |
| C-TERMINAL MODIFICATION | Conjugation with fluorescein by C-terminal Gly Cys amide |
| UPTAKE EFFICIENCY | Moderate relative to Tat-(48–60) peptide |
| PROPOSED UPTAKE MECHANISM | Non-endocytic pathway |
| INVITRO/INVIVO | In vitro |
| CELL LINE | RAW 264.7 |
| CARGO | Fluorophore (fluorescein) |
| PMID | 11084031 |
| PATENT | Unknown |
| LENGTH | 19 |
| Secondary Structure | CCSHHHHHHHTTHHHHTTC |
| SMILES | N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CS)C=O |
| Tertiary Structure (Technique) | View in Jmol OR Download Structure (PEPstrMOD) |