This page gives details of CPPsite entry with ID 1493 |
Primary information | |
---|---|
CPPsite ID | 1493 |
PEPTIDE SEQUENCE | TRSSRAGLQWPVGRVHRLLRKGGC |
PEPTIDE NAME | BF2d |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Antimicrobial |
SUB CELLULAR LOCALIZATION | Cytosol and nucleus |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Conjugation with Texas Red |
UPTAKE EFFICIENCY | Comparable to Tat (47-57) |
PROPOSED UPTAKE MECHANISM | Unknown probably non endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa or TM12 cells |
CARGO | Fluorophore (Texas Red) |
PMID | 12417587 |
PATENT | Unknown |
LENGTH | 24 |
Secondary Structure | CCCCTTTSCSCGGGGGTSHHHHCC |
SMILES | N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |