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This page gives details of CPPsite entry with ID 1803
Primary information
CPPsite ID1803
PEPTIDE SEQUENCERQIKIWFQNRRMKWKK
PEPTIDE NAMEPenetratin {pAntp-(43-58)}
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONConjugation with rhodamine B
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLess than polyarginine but greater tha Tat and tra
PROPOSED UPTAKE MECHANISMUnknown
INVITRO/INVIVOIn vitro
CELL LINECHO K1, HeLa, A549 cells
CARGOFluorophore (rhodamine)
PMID15937518
PATENTUnknown
LENGTH16
Secondary StructureCCCSSHHHHHHSSSCC
SMILES[NH3][C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCC[NH3])CCCC[NH3])Cc1c[nH]c2c1cccc2)CCCC[NH3])CCSC)CCCNC(=[NH2])N)CCCNC(=[NH2])N)CC(=O)N)CCC(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C)CCCC[NH3])[C@H](CC)C)CCC(=O)N)CCCNC(=[NH2])N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (Experimentally determined structure from PDB)