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This page gives details of CPPsite entry with ID 1832
Primary information
CPPsite ID1832
PEPTIDE SEQUENCETRQARRNRRRRWRERQRGC
PEPTIDE NAMEHIV-1 Rev (34-50)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUnknown
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with Alexa 488 at glycyl cysteine sequence
UPTAKE EFFICIENCY2.5–6.6 times more than the Tat (48–60) peptid
PROPOSED UPTAKE MECHANISMUnknown
INVITRO/INVIVOIn vitro
CELL LINECHO-K1, HeLa and Jurkat
CARGOFluorophore (Alexa-488)
PMID19707187
PATENTUnknown
LENGTH19
Secondary StructureCHHHHHHHHHHHHHHHTTC
SMILESN[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CS)C=O
Tertiary Structure
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  (PEPstrMOD)